Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.56 |
| ▸ | CA12 | O43570 | 5/20 | 0.56 |
| ▸ | CA9 | Q16790 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20850459 | 0.87 | CA12 (0.67) | CA2CA12CA9TSHRCYP2D6 | |
| SCHEMBL14869494 | 0.86 | APP (0.43) | CA2CA12CA9ALDH1A1HPGD | |
| SCHEMBL20850531 | 0.81 | GPR68 (0.45) | CA2CA12CA9ALDH1A1HPGD | |
| SCHEMBL14869738 | 0.79 | HRH4 (0.53) | ALDH1A1HSD17B10NPSR1ADORA2AHTR2B | |
| SCHEMBL31453478 | 0.79 | MAPK1 (0.55) | ALDH1A1HPGDNPSR1ADORA2AHTR2B | |
| SCHEMBL12925543 | 0.78 | HSD17B10 (0.45) | CA2CA12CA9ALDH1A1HPGD | |
| SCHEMBL20850722 | 0.77 | GPR68 (0.47) | CA2CA9NPSR1ADORA2AHTR2B | |
| SCHEMBL28628643 | 0.76 | HSPA5 (0.48) | CA2CA12CA9TSHRALDH1A1 | |
| SCHEMBL14869519 | 0.76 | CA1 (0.47) | CA2CA9ADORA2AHTR2BGPR68 | |
| SCHEMBL14869522 | 0.74 | ADORA2A (0.41) | CA2CA12CA9TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2504320-B1 | Melamine based mannich-compounds and a process for obtaining the same | BOREALIS AGROLINZ MELAMINE (AT) | 2015-10-14 | — | — | EP | disclosed |
| US-8802848-B2 | Melamine based mannich-compounds and a process for obtaining the same | BOREALIS AGROLINZ MELAMINE GMBH (AT) | 2014-08-12 | — | — | US | disclosed |
| US-20120277429-A1 | Melamine Based Mannich-Compounds and a Process for Obtaining the Same | BOREALIS AGROLINZ MELAMINE GMBH (AT) | 2012-11-01 | — | — | US | disclosed |
| EP-2504320-A1 | MELAMINE BASED MANNICH-COMPOUNDS AND A PROCESS FOR OBTAINING THE SAME | Borealis Agrolinz Melamine GmbH (AT) | 2012-10-03 | — | — | EP | disclosed |
| EP-2332926-A1 | Melamine based Mannich-compounds and a process for obtaining the same | Borealis Agrolinz Melamine GmbH (AT) | 2011-06-15 | — | — | EP | disclosed |
| WO-2011061220-A1 | MELAMINE BASED MANNICH-COMPOUNDS AND A PROCESS FOR OBTAINING THE SAME | BOREALIS AGROLINZ MELAMINE GMBH (AT) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277429-A1 | Melamine Based Mannich-Compounds and a Process for Obtaining the Same | MAN2A1, MANBA, MAN2B2 | CA2 3158/4885CA12 515/4885CA9 1619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.