Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21610034 | 0.77 | MAPT (0.52) | CA12CA9MAPTMEN1KMT2A | |
| SCHEMBL6451291 | 0.77 | MAPT (0.52) | CA12CA9MAPTMEN1KMT2A | |
| SCHEMBL6451289 | 0.77 | MAPT (0.52) | CA12CA9MAPTMEN1KMT2A | |
| SCHEMBL9176722 | 0.63 | SMN1; SMN2 (0.72) | MAPTMEN1KMT2ANPC1GBA1 | |
| SCHEMBL2921221 | 0.61 | JAK2 (0.57) | MAPTMEN1KMT2ANPC1KDM4E | |
| Biphenyl SCHEMBL27937069 | 0.60 | MEN1 (0.72) | CA12CA9MAPTMEN1KMT2A | |
| SCHEMBL12124929 | 0.60 | RAB9A (0.69) | CA12CA9MAPTMEN1KMT2A | |
| SCHEMBL18764387 | 0.60 | MAPT (0.85) | MAPTMEN1KMT2ANPC1GBA1 | |
| SCHEMBL16453466 | 0.60 | MEN1 (0.58) | MAPTMEN1KMT2ANPC1GBA1 | |
| SCHEMBL24106782 | 0.59 | MEN1 (0.70) | CA12CA9MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016187046-A1 | SURVIVIN-TARGETING ANTI-TUMOR AGENTS AND USES THEREOF | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2016-11-24 | — | — | WO | disclosed |