Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510416 | 1.00 | NR1H2 (0.44) | NR1H2SMN1; SMN2HSD17B10CHRM2CHRM1 | |
| SCHEMBL21408982 | 0.94 | SMN1; SMN2 (0.43) | NR1H2SMN1; SMN2HSD17B10CHRM2CHRM1 | |
| SCHEMBL28500054 | 0.94 | SMN1; SMN2 (0.43) | NR1H2SMN1; SMN2HSD17B10CHRM2CHRM1 | |
| SCHEMBL27230113 | 0.94 | SMN1; SMN2 (0.43) | NR1H2SMN1; SMN2HSD17B10CHRM2CHRM1 | |
| SCHEMBL21408983 | 0.94 | SMN1; SMN2 (0.43) | NR1H2SMN1; SMN2HSD17B10CHRM2CHRM1 | |
| SCHEMBL27207827 | 0.94 | SMN1; SMN2 (0.43) | NR1H2SMN1; SMN2HSD17B10CHRM2CHRM1 | |
| SCHEMBL28504704 | 0.91 | SMN1; SMN2 (0.38) | NR1H2SMN1; SMN2HSD17B10CHRM2CHRM1 | |
| SCHEMBL28504723 | 0.91 | SMN1; SMN2 (0.38) | NR1H2SMN1; SMN2HSD17B10CHRM2CHRM1 | |
| SCHEMBL28504724 | 0.91 | SMN1; SMN2 (0.38) | NR1H2SMN1; SMN2HSD17B10CHRM2CHRM1 | |
| SCHEMBL1239390 | 0.87 | SMN1; SMN2 (0.49) | NR1H2SMN1; SMN2HSD17B10CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160338999-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2016-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160338999-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, PYGL, HCCS | NR1H2 156/4885SMN1; SMN2 4352/4885HSD17B10 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.