Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.76 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.76 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.76 |
| ▸ | GBA1 | P04062 | 3/20 | 0.59 |
| ▸ | GLB1 | P16278 | 3/20 | 0.58 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17697370 | 0.88 | HDAC4 (0.79) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL15259321 | 0.88 | HDAC4 (0.79) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL29524676 | 0.88 | HDAC4 (0.79) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL15507473 | 0.88 | HDAC4 (0.79) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL15515796 | 0.88 | HDAC4 (0.79) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL8016351 | 0.88 | HDAC4 (0.79) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL15515613 | 0.88 | HDAC4 (0.79) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL591663 | 0.88 | HDAC4 (0.79) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL18257191 | 0.88 | HDAC4 (0.79) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL1712988 | 0.88 | HDAC4 (0.79) | HDAC4HDAC10HDAC6HDAC5GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016187544-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING CANCER | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-11-24 | — | — | WO | disclosed |