Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17446680 | 0.92 | MDM4 (0.47) | MDM4TP53MDM2KMT2ACASP3 | |
| SCHEMBL30502990 | 0.90 | KMT2A (0.47) | MDM4TP53KMT2ACASP3SLC17A5 | |
| SCHEMBL30538853 | 0.90 | MDM4 (0.54) | MDM4TP53MDM2BACE1KMT2A | |
| SCHEMBL5972648 | 0.90 | MDM4 (0.54) | MDM4TP53MDM2BACE1KMT2A | |
| SCHEMBL9091221 | 0.90 | KMT2A (0.49) | MDM4TP53MDM2BACE1KMT2A | |
| SCHEMBL17446822 | 0.88 | PTPN1 (0.45) | MDM4TP53KMT2A | |
| SCHEMBL19177098 | 0.86 | MDM4 (0.42) | MDM4TP53MDM2KMT2ACASP3 | |
| SCHEMBL29579138 | 0.86 | MDM4 (0.49) | MDM4TP53KMT2ACASP3SLC17A5 | |
| SCHEMBL29579031 | 0.86 | MDM4 (0.43) | MDM4TP53MDM2BACE1KMT2A | |
| SCHEMBL8695710 | 0.85 | MDM4 (0.45) | MDM4TP53KMT2ACASP3SLC17A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016185200-A1 | ANTIBACTERIAL AGENT | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2016-11-24 | — | — | WO | disclosed |