Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.57 |
| ▸ | CTSL | P07711 | 5/20 | 0.54 |
| ▸ | CTSS | P25774 | 4/20 | 0.54 |
| ▸ | CTSB | P07858 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8276388 | 0.89 | CTSK (0.56) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL8276393 | 0.89 | CTSK (0.56) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL18257510 | 0.89 | CTSK (0.56) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL14011286 | 0.85 | CTSK (0.64) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL8353955 | 0.84 | CTSK (0.62) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL10100520 | 0.83 | CTSK (0.61) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL3333284 | 0.82 | CTSK (0.60) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL7292473 | 0.82 | CTSK (0.60) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL7267991 | 0.81 | CTSK (0.56) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL25465567 | 0.81 | CTSK (0.58) | CTSKCTSLCTSSCTSBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016185450-A1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS PRIVATE LIMITED (IN) | 2016-11-24 | — | — | WO | disclosed |