Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18257501 | 1.00 | CA1 (0.55) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL13884652 | 0.86 | CA1 (0.54) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL20815918 | 0.86 | CA1 (0.54) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL20825231 | 0.86 | CA1 (0.54) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL13884654 | 0.86 | CA1 (0.54) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL8080058 | 0.86 | CA1 (0.54) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL13893436 | 0.86 | CA1 (0.54) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL18786179 | 0.84 | CTSK (0.58) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL787984 | 0.83 | CA1 (0.57) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL13932833 | 0.82 | CA1 (0.74) | CA1CA2CA7CTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016185450-A1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS PRIVATE LIMITED (IN) | 2016-11-24 | — | — | WO | disclosed |