SCHEMBL1825820

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1824632	0.88	PPARG (0.45)	MAPTALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL1826558	0.86	TDP1 (0.50)	TDP1MAPTMAOBNPC1RAB9A
	SCHEMBL1825231	0.83	CA2 (0.39)	MAPTALDH1A1MEN1KMT2ARECQL
	SCHEMBL1821226	0.82	MAPT (0.47)	TDP1MAPTNPC1RAB9AALDH1A1
	SCHEMBL1827681	0.82	TDP1 (0.46)	TDP1MAPTMAOBNPC1RAB9A
	SCHEMBL10180331	0.81	TDP1 (0.54)	TDP1MAPTMAOBNPC1RAB9A
	SCHEMBL1826441	0.79	TDP1 (0.51)	TDP1MAPTMAOBNPC1RAB9A
	SCHEMBL2452793	0.79	MAPK1 (0.40)	ALDH1A1MEN1KMT2AMAPK1
	SCHEMBL2986520	0.78	TDP1 (0.61)	TDP1MAPTMAOBNPC1RAB9A
	SCHEMBL3838595	0.78	TDP1 (0.61)	TDP1MAPTMAOBNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.