Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.83 |
| ▸ | ITGAV | P06756 | 20/20 | 0.83 |
| ▸ | ITGB6 | P18564 | 11/20 | 0.83 |
| ▸ | ITGB5 | P18084 | 6/20 | 0.83 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.83 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.58 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.57 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1825834 | 1.00 | ITGB3 (0.83) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL6178864 | 0.91 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL6178862 | 0.91 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL1824189 | 0.87 | ITGB3 (0.86) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL1824185 | 0.87 | ITGB3 (0.86) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2841497 | 0.87 | ITGAV (0.74) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL21562843 | 0.86 | ITGAV (0.68) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2841970 | 0.85 | ITGB3 (0.75) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL7507810 | 0.81 | ITGB3 (0.76) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL7507825 | 0.81 | ITGB3 (0.76) | ITGB3ITGAVITGB6ITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4685307-B2 | — | — | 2011-05-18 | — | — | JP | claimed |
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | claimed |
| EP-1218005-B1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-12-15 | — | — | EP | claimed |
| JP-2003508516-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1218005-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-10-09 | — | — | EP | claimed |
| EP-1218005-A2 | VITRONECTIN RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2002-07-03 | — | — | EP | claimed |
| WO-2001017959-A2 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-03-15 | — | — | WO | claimed |
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |
| EP-1218005-B1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1218005-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-10-09 | — | — | EP | disclosed |
| EP-1218005-A2 | VITRONECTIN RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001017959-A2 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-03-15 | — | — | WO | disclosed |