SCHEMBL18258693

SCHEMBL18258693

O=c1[nH]c(-c2c(O)cccc2Cl)nc2ccccc12

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GUSB P08236 12/20 0.81
HPGD P15428 2/20 0.63
KDM4E B2RXH2 2/20 0.63
TNKS O95271 5/20 0.56
TNKS2 Q9H2K2 5/20 0.56
PARP1 P09874 4/20 0.56
PARP2 Q9UGN5 1/20 0.56
MAPT P10636 2/20 0.50
ALDH1A1 P00352 1/20 0.50
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 1/20 0.50
APOBEC3G Q9HC16 1/20 0.50
CYP1A1 P04798 2/20 0.49
CYP1B1 Q16678 2/20 0.49
LMNA P02545 2/20 0.49
CYP1A2 P05177 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16008227 0.90 GUSB (1.00) GUSBHPGDKDM4ETNKSTNKS2
SCHEMBL16007844 0.83 GUSB (1.00) GUSBHPGDKDM4ETNKSTNKS2
SCHEMBL31138463 0.83 GUSB (0.81) GUSBHPGDKDM4ETNKSTNKS2
SCHEMBL18258708 0.81 GUSB (0.76) GUSBHPGDKDM4ETNKSTNKS2
SCHEMBL1623659 0.80 GUSB (0.75) GUSBTNKSTNKS2PARP1PARP2
SCHEMBL296097 0.78 GUSB (1.00) GUSBHPGDKDM4ETNKSTNKS2
SCHEMBL8623127 0.78 GUSB (1.00) GUSBHPGDKDM4ETNKSTNKS2
SCHEMBL30259689 0.78 GUSB (1.00) GUSBHPGDKDM4ETNKSTNKS2
SCHEMBL29890314 0.78 GUSB (1.00) GUSBHPGDKDM4ETNKSTNKS2
SCHEMBL11283678 0.77 GUSB (0.81) GUSBHPGDKDM4ETNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170012218-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME NANO CMS CO., LTD. (KR) 2017-01-12 US claimed
EP-3098284-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME Nano CMS Co., Ltd. (KR) 2016-11-30 EP claimed
US-20170012218-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME NANO CMS CO., LTD. (KR) 2017-01-12 US disclosed
US-20170012218-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME NANO CMS CO., LTD. (KR) 2017-01-12 US disclosed
US-20170012218-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME NANO CMS CO., LTD. (KR) 2017-01-12 US disclosed
EP-3098284-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME Nano CMS Co., Ltd. (KR) 2016-11-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170012218-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME SUN2, TYR, SQLE GUSB 1639/4885HPGD 168/4885KDM4E 1890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.