Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 11/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | TNKS | O95271 | 5/20 | 0.63 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.63 |
| ▸ | PARP1 | P09874 | 3/20 | 0.63 |
| ▸ | PDE5A | O76074 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29890314 | 1.00 | GUSB (1.00) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL30259689 | 1.00 | GUSB (1.00) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL15691367 | 0.86 | GUSB (0.82) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL31710757 | 0.86 | GUSB (0.76) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL18258694 | 0.86 | GUSB (0.76) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL31066914 | 0.85 | GUSB (1.00) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL31066916 | 0.85 | GUSB (1.00) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL16007727 | 0.85 | GUSB (1.00) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL11746423 | 0.84 | GUSB (0.74) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL18258699 | 0.84 | GUSB (0.78) | GUSBHPGDKDM4ETNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313156-B1 | DISULFIDE-BASED PRODRUG COMPOUNDS | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2025-08-06 | — | — | EP | claimed |
| US-20240207414-A1 | DISULFIDE-BASED PRODRUG COMPOUND | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2024-06-27 | — | — | US | claimed |
| US-20240156965-A1 | DICHALCOGENIDE PRODRUGS | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2024-05-16 | — | — | US | claimed |
| EP-4320124-A1 | DICHALCOGENIDE PRODRUGS | Ludwig-Maximilians-Universität München (DE) | 2024-02-14 | — | — | EP | claimed |
| EP-4313156-A1 | DISULFIDE-BASED PRODRUG COMPOUNDS | Ludwig-Maximilians-Universität München (DE) | 2024-02-07 | — | — | EP | claimed |
| EP-4071148-A1 | DICHALCOGENIDE PRODRUGS | Ludwig-Maximilians-Universität München (DE) | 2022-10-12 | — | — | EP | claimed |
| EP-4062942-A1 | DISULFIDE-BASED PRODRUG COMPOUNDS | Ludwig-Maximilians-Universität München (DE) | 2022-09-28 | — | — | EP | claimed |
| EP-3526208-B1 | NEW COMPOUNDS AND USES THEREOF FOR DETECTION OF TARGET MOLECULES IN A SAMPLE | UNIV GENEVE (CH) | 2021-03-24 | — | — | EP | claimed |
| CN-106632088-A | Aggregation-induced emission probe based on quinazolinones compound as well as preparation method and application of aggregation-induced emission probe | 华南理工大学 | 2017-05-10 | — | — | CN | claimed |
| EP-2366696-A1 | Process for producing 4-aminoquinazolines | Vertex Pharmaceuticals Incorporated (US) | 2011-09-21 | — | — | EP | claimed |
| US-20060166963-A1 | Processes for producing 4-aminoquinazolines | VERTEX PHARMACEUTICALS INCORPORATED | 2006-07-27 | — | — | US | claimed |
| CN-1708306-A | Quinazolinone compounds as calcilytics | NPS PHARMA INC (US) | 2005-12-14 | — | — | CN | claimed |
| EP-4313156-B1 | DISULFIDE-BASED PRODRUG COMPOUNDS | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2025-08-06 | — | — | EP | disclosed |
| US-20250092437-A1 | DISEASE DETECTION WITH COMBINATORIAL BIOMARKERS | Sunbird Bio, Inc. | 2025-03-20 | — | — | US | disclosed |
| US-20240207414-A1 | DISULFIDE-BASED PRODRUG COMPOUND | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2024-06-27 | — | — | US | disclosed |
| US-20240156965-A1 | DICHALCOGENIDE PRODRUGS | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2024-05-16 | — | — | US | disclosed |
| EP-0641351-B1 | ENZYMATIC ANALYSIS USING SUBSTRATES THAT YIELD FLUORESCENT PRECIPITATES | MOLECULAR PROBES INC (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5443986-A | Enzymatic analysis using substrates that yield fluorescent precipitates | MOLECULAR PROBES, INC. (US) | 1995-08-22 | — | — | US | disclosed |
| US-5316906-A | Fluorescent dyes for substrates | MOLECULAR PROBES, INC. (US) | 1994-05-31 | — | — | US | disclosed |
| US-5149138-A | Dissolving in halocarbon solvent | ZEMSKY MICHAEL D | 1992-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166963-A1 | Processes for producing 4-aminoquinazolines | CACNA1I, CACNA1G, CACNA1B | GUSB 4518/4885HPGD 603/4885KDM4E 1377/4885 |
| US-20240207414-A1 | DISULFIDE-BASED PRODRUG COMPOUND | CBS, MSR1, P4HB | GUSB 162/4885HPGD 281/4885KDM4E 4718/4885 |
| US-20240156965-A1 | DICHALCOGENIDE PRODRUGS | DHCR7, DECR1, CYP27A1 | GUSB 58/4885HPGD 483/4885KDM4E 4690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.