Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 13/20 | 0.40 |
| ▸ | TACR1 | P25103 | 3/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623761 | 0.91 | CETP (0.40) | CETPTACR1MDM2 | |
| SCHEMBL5046633 | 0.90 | CETP (0.39) | CETPTACR1MDM2 | |
| SCHEMBL5043477 | 0.89 | CETP (0.38) | CETPTACR1MDM2 | |
| SCHEMBL18259016 | 0.83 | CETP (0.37) | CETPTACR1 | |
| SCHEMBL18259018 | 0.82 | CETP (0.36) | CETPTACR1 | |
| SCHEMBL5624654 | 0.82 | CETP (0.37) | CETPTACR1MDM2 | |
| SCHEMBL5049263 | 0.79 | TACR1 (0.35) | TACR1MDM2 | |
| SCHEMBL5042804 | 0.77 | CETP (0.36) | CETPMDM2 | |
| SCHEMBL5043405 | 0.77 | SCN2A (0.31) | — | |
| SCHEMBL5046459 | 0.76 | CETP (0.41) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981342-B1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDYS LAB LTD DR (IN) | 2016-11-30 | — | — | EP | disclosed |