Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 12/20 | 0.37 |
| ▸ | TACR1 | P25103 | 3/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623758 | 0.90 | CETP (0.37) | CETPTACR1ALDH1A1L3MBTL1PTGDR2 | |
| SCHEMBL5046631 | 0.90 | CETP (0.37) | CETPTACR1ALDH1A1L3MBTL1PTGDR2 | |
| SCHEMBL5043473 | 0.88 | ALDH1A1 (0.37) | CETPTACR1ALDH1A1L3MBTL1PTGDR2 | |
| SCHEMBL18259018 | 0.85 | CETP (0.36) | CETPTACR1ALDH1A1L3MBTL1PDE10A | |
| SCHEMBL18259017 | 0.83 | CETP (0.40) | CETPTACR1 | |
| SCHEMBL5624651 | 0.81 | CETP (0.34) | CETPTACR1ALDH1A1L3MBTL1 | |
| SCHEMBL5049262 | 0.77 | TACR1 (0.37) | CETPTACR1 | |
| SCHEMBL5042803 | 0.76 | CETP (0.33) | CETPALDH1A1L3MBTL1 | |
| SCHEMBL5046458 | 0.75 | CETP (0.42) | CETP | |
| SCHEMBL5623765 | 0.75 | CETP (0.37) | CETPTACR1ALDH1A1L3MBTL1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981342-B1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDYS LAB LTD DR (IN) | 2016-11-30 | — | — | EP | disclosed |