Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ENPP1 | P22413 | 5/20 | 0.45 |
| ▸ | ENPP3 | O14638 | 4/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 6/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1823722 | 0.79 | EGFR (0.48) | EGFRENPP1ENPP3MEN1KMT2A | |
| SCHEMBL3571453 | 0.79 | EGFR (0.46) | EGFRENPP1ENPP3MEN1KMT2A | |
| SCHEMBL1822824 | 0.78 | EGFR (0.45) | EGFRENPP1ENPP3ENPP2ALDH1A1 | |
| SCHEMBL1825979 | 0.77 | EGFR (0.46) | EGFRENPP1ENPP3MEN1KMT2A | |
| SCHEMBL1827842 | 0.76 | EGFR (0.43) | EGFRALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL1825630 | 0.76 | EGFR (0.43) | EGFRALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL1824701 | 0.76 | EGFR (0.43) | EGFRALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL1825617 | 0.75 | ABCB1 (0.44) | EGFRALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL1822865 | 0.75 | P2RX7 (0.47) | EGFRCA2CA9 | |
| SCHEMBL2295360 | 0.74 | ENPP1 (0.49) | EGFRENPP1ENPP3ENPP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161254-B1 | Intermediate for preparing a biaryl compound | SUMITOMO CHEMICAL CO (JP) | 2014-08-13 | — | — | EP | disclosed |
| EP-1481967-B1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2011-05-04 | — | — | EP | disclosed |
| EP-2161254-A1 | Intermediate for preparing a biaryl compound | Sumitomo Chemical Company, Limited (JP) | 2010-03-10 | — | — | EP | disclosed |