SCHEMBL1826151

SCHEMBL1826151

C/C=N/c1c(C)cccc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.41
MEN1 O00255 1/20 0.41
HSP90AA1 P07900 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP2A6 P11509 2/20 0.39
CYP1A2 P05177 1/20 0.39
TSHR P16473 2/20 0.38
ACHE P22303 1/20 0.38
ALDH1A1 P00352 5/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
GRIN2D O15399 2/20 0.36
GRIN3B O60391 2/20 0.36
GRIN1 Q05586 2/20 0.36
GRIN2A Q12879 2/20 0.36
GRIN2B Q13224 2/20 0.36
GRIN2C Q14957 2/20 0.36
GRIN3A Q8TCU5 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1826153 1.00 ATM (0.41) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL23706906 1.00 ATM (0.41) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL21130456 0.84 ATM (0.46) ATMMEN1HSP90AA1KMT2ACYP1A2
SCHEMBL29593780 0.84 MEN1 (0.35) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL24851075 0.83 ATM (0.31) ATMMEN1HSP90AA1KMT2ACYP1A2
SCHEMBL4350537 0.81 ATM (0.43) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL4350534 0.81 ATM (0.43) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL20842399 0.81 CYP2C9 (0.35) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL24952842 0.81 MEN1 (0.33) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL21649861 0.81 ALDH1A1 (0.33) ATMMEN1HSP90AA1KMT2ACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987393-B2 Catalyst component for the polymerization of olefins having a guanidinate ligand LANXESS ELASTOMERS B.V. (NL) 2015-03-24 US disclosed
US-20130079478-A1 CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS HAVING A GUANIDINATE LIGAND LANXESS ELASTOMERS B.V. 2013-03-28 US disclosed
EP-2496612-A1 CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS HAVING A GUANIDINATE LIGAND Lanxess Elastomers B.V. (NL) 2012-09-12 EP disclosed
WO-2011054927-A1 CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS HAVING A GUANIDINATE LIGAND DSM IP ASSETS B.V. (NL) 2011-05-12 WO disclosed
EP-2319874-A1 Catalyst component for the polymerization of olefins having a guanidinate ligand DSM IP Assets B.V. (NL) 2011-05-11 EP disclosed
US-7612245-B2 converting 1,3-butadiene to cis-2-butene in presence of a hydrogenation catalyst mixture containing iron octanoate, triethylaluminium, 2,3-bis(2,6-dimethylphenylimino)butane; catalyst selectivity INSTITUT FRANCAIS DU PETROLE (FR) 2009-11-03 US disclosed
EP-0065712-B1 N-(1-ALKENYL)-CHLOROACETIC-ACID ANILIDES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES AND REGULATORS OF PLANT GROWTH BAYER AG (DE) 1987-07-22 EP disclosed
US-4599448-A Novel N-(1-alkenyl)-chloroacetanilides as herbicides and plant growth regulators BAYER AKTIENGESELLSCHAFT (DE) 1986-07-08 US disclosed
EP-0075167-B1 N-(1-ALKENYL)-CARBOXANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1985-02-13 EP disclosed
EP-0075167-A2 N-(1-alkenyl)-carboxanilides, process for their preparation and their use as fungicides BAYER AG (DE) 1983-03-30 EP disclosed
EP-0065712-A2 N-(1-alkenyl)-chloroacetic-acid anilides, process for their preparation, and their use as herbicides and regulators of plant growth BAYER AG (DE) 1982-12-01 EP disclosed
EP-0036544-A1 Method for the preparation of substituted N-azolyl-methyl-halogeno-acetanilides BAYER AG (DE) 1981-09-30 EP disclosed