Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1781857 | 1.00 | CCR2 (1.00) | CCR2 | |
| SCHEMBL14237216 | 1.00 | CCR2 (1.00) | CCR2 | |
| SCHEMBL1827584 | 1.00 | CCR2 (1.00) | CCR2 | |
| SCHEMBL14237163 | 1.00 | CCR2 (1.00) | CCR2 | |
| SCHEMBL1781951 | 0.90 | CCR2 (0.81) | CCR2 | |
| SCHEMBL1781364 | 0.85 | CCR2 (1.00) | CCR2 | |
| SCHEMBL14237076 | 0.85 | CCR2 (1.00) | CCR2 | |
| SCHEMBL1779544 | 0.85 | CCR2 (1.00) | CCR2 | |
| SCHEMBL1781696 | 0.85 | CCR2 (0.73) | CCR2 | |
| SCHEMBL14237046 | 0.85 | CCR2 (1.00) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318352-A2 | CYCLOHEXENYL MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010009068-A2 | CYCLOHEXENYL MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-01-21 | — | — | WO | disclosed |