Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.61 |
| ▸ | XDH | P47989 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30676032 | 0.85 | ALDH1A1 (0.61) | KDM4EMEN1ALOX12KMT2AKDM4C | |
| SCHEMBL26926668 | 0.85 | ALDH1A1 (0.61) | KDM4EMEN1ALOX12KMT2AKDM4C | |
| SCHEMBL26926346 | 0.83 | KDM4E (0.55) | KDM4EMEN1ALOX12KMT2AKDM4C | |
| SCHEMBL30676042 | 0.83 | KDM4E (0.55) | KDM4EMEN1ALOX12KMT2AKDM4C | |
| SCHEMBL26926475 | 0.82 | KDM4E (0.54) | KDM4EMEN1ALOX12KMT2AKDM4C | |
| SCHEMBL30676033 | 0.82 | KDM4E (0.54) | KDM4EMEN1ALOX12KMT2AKDM4C | |
| SCHEMBL30676045 | 0.82 | MEN1 (0.56) | KDM4EMEN1ALOX12KMT2AKDM4C | |
| SCHEMBL26926176 | 0.82 | MEN1 (0.56) | KDM4EMEN1ALOX12KMT2AKDM4C | |
| SCHEMBL18262990 | 0.80 | KDM4E (0.81) | KDM4EMEN1ALOX12KMT2AKDM4C | |
| SCHEMBL30676055 | 0.78 | KDM4E (0.55) | KDM4EMEN1ALOX12KMT2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016187667-A1 | FUNCTIONALISED AND SUBSTITUTED INDOLES AS ANTI-CANCER AGENTS | NOVOGEN LIMITED (AU) | 2016-12-01 | — | — | WO | disclosed |