Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.45 |
| ▸ | LMNA | P02545 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 9/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.45 |
| ▸ | HTT | P42858 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL224253 | 1.00 | MAPT (0.45) | MAPTLMNAMEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL30999654 | 1.00 | MAPT (0.45) | MAPTLMNAMEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL3020867 | 1.00 | MAPT (0.45) | MAPTLMNAMEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL31402544 | 1.00 | MAPT (0.45) | MAPTLMNAMEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL31402545 | 1.00 | MAPT (0.45) | MAPTLMNAMEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL31402546 | 1.00 | MAPT (0.45) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL22489411 | 0.99 | MAPT (0.45) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL3131736 | 0.99 | MAPT (0.45) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL766931 | 0.99 | MAPT (0.45) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL7604087 | 0.99 | MAPT (0.45) | MAPTLMNAMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3302576-B1 | MULTIVALENT TARGETING FLUORESCENT TRACER IN THE NEAR INFRARED RANGE FOR OPTICAL IMAGING | FLUOPTICS (FR) | 2021-04-28 | — | — | EP | disclosed |
| US-10857242-B2 | Multivalent targeting fluorescent tracer in the near infrared range for optical imaging | FLUOPTICS (FR) | 2020-12-08 | — | — | US | disclosed |
| US-20180147303-A1 | MULTIVALENT TARGETING FLUORESCENT TRACER IN THE NEAR INFRARED RANGE FOR OPTICAL IMAGING | FLUOPTICS (FR) | 2018-05-31 | — | — | US | disclosed |
| EP-3302576-A1 | MULTIVALENT TARGETING FLUORESCENT TRACER IN THE NEAR INFRARED RANGE FOR OPTICAL IMAGING | Fluoptics (FR) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016189004-A1 | MULTIVALENT TARGETING FLUORESCENT TRACER IN THE NEAR INFRARED RANGE FOR OPTICAL IMAGING | FLUOPTICS (FR) | 2016-12-01 | — | — | WO | disclosed |