SCHEMBL1826487

SCHEMBL1826487

C=CCc1cccc(OP(=O)(O)Oc2ccccc2)c1CC=C

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.39
KDM4E B2RXH2 3/20 0.38
GPR84 Q9NQS5 1/20 0.37
ALDH1A1 P00352 2/20 0.36
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ANPEP P15144 1/20 0.33
LAP3 P28838 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5824255 0.92 GABRA1 (0.36) SRCKDM4EGPR84ALDH1A1GABRA1
SCHEMBL2143338 0.90 SRC (0.39) SRCKDM4EGPR84ALDH1A1ANPEP
SCHEMBL2732358 0.89 KDM4E (0.43) SRCKDM4EGPR84ALDH1A1
SCHEMBL407519 0.83 INPPL1 (0.47) SRCKDM4EALDH1A1GABRA1GABRB2
SCHEMBL29044426 0.82 INPPL1 (0.46) SRCKDM4EALDH1A1GABRA1GABRB2
SCHEMBL16779898 0.82 GABRA1 (0.36) SRCKDM4EALDH1A1GABRA1GABRB2
SCHEMBL3474948 0.81 KDM4E (0.45) KDM4EALDH1A1
Phosphoric Acid SCHEMBL3968523 0.80 GABRA1 (0.43) KDM4EALDH1A1GABRA1GABRB2MEN1
SCHEMBL407518 0.80 GABRA1 (0.40) KDM4EALDH1A1GABRA1GABRB2MEN1
SCHEMBL278393 0.78 HRH1 (0.46) KDM4EALDH1A1GABRA1GABRB2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4683726-B2 2011-05-18 JP claimed
JP-2002526571-A 2002-08-20 JP claimed
EP-1115728-A1 TRIARYL PHOSPHATE ESTER COMPOSITION Akzo Nobel N.V. (NL) 2001-07-18 EP claimed
US-6242631-B1 Triaryl phosphate ester composition AKZO NOBEL NV (NL) 2001-06-05 US claimed
WO-2000017210-A1 TRIARYL PHOSPHATE ESTER COMPOSITION AKZO NOBEL N.V. (NL) 2000-03-30 WO claimed
EP-0573082-B1 Triaryl phosphate ester composition and process for its preparation FMC CORP (US) 1998-01-14 EP claimed
EP-0573082-A2 Triaryl phosphate ester composition and process for its preparation FMC CORPORATION (US) 1993-12-08 EP claimed
US-5206404-A Purifying by passing through thin film evaporators; oxidation, wear, heat, hydroytic stability FMC CORPORATION (US) 1993-04-27 US claimed
JP-6009661-A None JP disclosed
CN-110337484-B Antimony-free flame-retardant epoxy resin composition 溴化合物有限公司 2022-05-24 CN disclosed
EP-3006543-B1 POLYFUNCTIONAL LUBRICANT COMPOSITION ADEKA CORP (JP) 2021-05-26 EP disclosed
EP-2446005-B1 ANTI-WEAR AGENTS WITH A REDUCED NEUROTOXICITY NYCO (FR) 2015-04-29 EP disclosed
EP-2446005-A1 ANTI-WEAR AGENTS WITH A REDUCED NEUROTOXICITY Nyco SA (FR) 2012-05-02 EP disclosed
US-20120101015-A1 ANTI-WEAR AGENTS WITH A REDUCED NEUROTOXICITY NYCO SA (FR) 2012-04-26 US disclosed
EP-0573082-B1 Triaryl phosphate ester composition and process for its preparation FMC CORP (US) 1998-01-14 EP disclosed
JP-H069661-A TRIALKYLPHOSPHATE ESTER COMPOSITION AND ITS PRODUCTION FMC CORP 1994-01-18 JP disclosed
EP-0573082-A2 Triaryl phosphate ester composition and process for its preparation FMC CORPORATION (US) 1993-12-08 EP disclosed
EP-0573082-A2 Triaryl phosphate ester composition and process for its preparation FMC CORPORATION (US) 1993-12-08 EP disclosed
US-5206404-A Purifying by passing through thin film evaporators; oxidation, wear, heat, hydroytic stability FMC CORPORATION (US) 1993-04-27 US disclosed
US-5206404-A Purifying by passing through thin film evaporators; oxidation, wear, heat, hydroytic stability FMC CORPORATION (US) 1993-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120101015-A1 ANTI-WEAR AGENTS WITH A REDUCED NEUROTOXICITY SSB, PRNP, TARDBP SRC 1974/4885KDM4E 4197/4885GPR84 3461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.