SCHEMBL18265151

SCHEMBL18265151

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nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
ALDH1A1 P00352 5/20 0.32
TDP1 Q9NUW8 2/20 0.32
LMNA P02545 1/20 0.32
SLC15A2 Q16348 1/20 0.32
HMGCR P04035 1/20 0.31
CHRM1 P11229 1/20 0.31
TBXA2R P21731 1/20 0.31
ADRA1A P35348 1/20 0.31
TRPA1 O75762 1/20 0.30
FFAR3 O14843 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9248985 0.81 ALDH1A1 (0.33) ALDH1A1TDP1TRPA1
Acetic Acid SCHEMBL8521559 0.80 FFAR3 (0.44) TSHRCYP2D6CYP2C19HIF1AALDH1A1
Acetic Acid SCHEMBL9779003 0.80 FFAR3 (0.44) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL1604126 0.79 ALDH1A1 (0.38) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL9747466 0.78 ALDH1A1 (0.46) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL176385 0.76 ALDH1A1 (0.35) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL461282 0.75 ALDH1A1 (0.32) ALDH1A1LMNA
Methylamine SCHEMBL28402560 0.75 TSHR (0.35) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL6394238 0.74 ALDH1A1 (0.33) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL11025729 0.73 CYP2D6 (0.41) TSHRCYP2D6CYP2C19HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115251518-A Outsole and method for producing an outsole 耐克创新有限合伙公司 2022-11-01 CN disclosed
US-20170096446-A1 Extended Triterpene Derivatives MYREXIS, INC. (US) 2017-04-06 US disclosed
US-9505800-B2 Extended triterpene derivatives MYREXIS, INC. (US) 2016-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170096446-A1 Extended Triterpene Derivatives BET1, PGGT1B, TMPO TSHR 4604/4885CYP2D6 417/4885CYP2C19 117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.