SCHEMBL18267273

SCHEMBL18267273

CN1C(=O)C(=Cc2ccc3c(c2)C(C)(C)c2cc(N(c4ccccc4)c4ccccc4)ccc2-3)C(=O)N(C)C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.40
APP P05067 2/20 0.40
SNCA P37840 1/20 0.40
ALDH1A1 P00352 8/20 0.40
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
RECQL P46063 1/20 0.39
KDM4C Q9H3R0 1/20 0.39
KDM4E B2RXH2 3/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
EP300 Q09472 1/20 0.38
RXFP1 Q9HBX9 1/20 0.37
POLB P06746 1/20 0.37
HPGD P15428 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20850195 0.84 LCK (0.44) MAPTAPPSNCAALDH1A1KMT2A
SCHEMBL20850219 0.83 MAPT (0.39) MAPTAPPSNCAALDH1A1KMT2A
SCHEMBL2719600 0.82 CA12 (0.54) MAPTAPPSNCAALDH1A1KMT2A
SCHEMBL18267270 0.81 MAPT (0.40) MAPTAPPSNCAALDH1A1KMT2A
SCHEMBL18267281 0.79 MAPT (0.39) MAPTALDH1A1KMT2AMEN1KDM4E
SCHEMBL13372219 0.78 ALDH1A1 (0.37) MAPTAPPALDH1A1KMT2AMEN1
SCHEMBL13414484 0.78 PDK2 (0.40) MAPTAPPALDH1A1KMT2AMEN1
SCHEMBL1103697 0.78 PDK2 (0.40) MAPTAPPALDH1A1KMT2AMEN1
SCHEMBL18267283 0.78 MIF (0.57) MAPTALDH1A1KMT2AMEN1RECQL
SCHEMBL2757066 0.77 PDK2 (0.43) MAPTAPPALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10361379-B2 Photoelectric conversion element, photosensor, and imaging device FUJIFILM CORPORATION (JP) 2019-07-23 US disclosed
US-20160351830-A1 PHOTOELECTRIC CONVERSION ELEMENT, PHOTOSENSOR, AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2016-12-01 US disclosed
US-20160351830-A1 PHOTOELECTRIC CONVERSION ELEMENT, PHOTOSENSOR, AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2016-12-01 US disclosed