Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 5/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 5/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1826788 | 0.88 | KMT2A (0.47) | CXCR2MAPTALDH1A1ENPP3ENPP1 | |
| SCHEMBL1821552 | 0.86 | PTGS1 (0.46) | TDP1ADAMTS4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2834868 | 0.85 | ADAMTS4 (0.52) | TDP1ADAMTS4CXCR2MAPTNPC1 | |
| SCHEMBL1345327 | 0.83 | ADAMTS4 (0.55) | TDP1ADAMTS4CXCR2MAPTNPC1 | |
| SCHEMBL2835298 | 0.83 | ADAMTS4 (0.55) | TDP1ADAMTS4CXCR2MAPTNPC1 | |
| SCHEMBL1345199 | 0.83 | ADAMTS4 (0.55) | TDP1ADAMTS4CXCR2MAPTNPC1 | |
| SCHEMBL2832246 | 0.83 | TDP1 (0.48) | TDP1ADAMTS4MAPTNPC1RAB9A | |
| SCHEMBL1827845 | 0.83 | MAPT (0.44) | TDP1ADAMTS4MAPTNPC1RAB9A | |
| SCHEMBL1824672 | 0.82 | TDP1 (0.53) | TDP1ADAMTS4CXCR2CXCR1MAPT | |
| SCHEMBL1825479 | 0.82 | CXCR2 (0.47) | TDP1CXCR2CXCR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481967-B1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2011-05-04 | — | — | EP | disclosed |