Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28774116 | 0.87 | CHRM1 (0.65) | CHRM1MAPK1ATMALDH1A1LMNA | |
| SCHEMBL31448036 | 0.78 | CHRM1 (0.73) | CHRM1MAPK1ATMALDH1A1LMNA | |
| SCHEMBL28602047 | 0.77 | CHRM1 (0.52) | CHRM1MAPK1ATMALDH1A1LMNA | |
| Ornidazole SCHEMBL15158378 | 0.76 | CHRM1 (1.00) | CHRM1MAPK1ATMALDH1A1LMNA | |
| Ornidazole SCHEMBL15158379 | 0.76 | CHRM1 (1.00) | CHRM1MAPK1ATMALDH1A1LMNA | |
| Ornidazole SCHEMBL43039 | 0.76 | CHRM1 (1.00) | CHRM1MAPK1ATMALDH1A1LMNA | |
| SCHEMBL16367357 | 0.76 | MAPK1 (0.60) | CHRM1MAPK1ATMALDH1A1LMNA | |
| Ornidazole SCHEMBL22773516 | 0.75 | CHRM1 (0.97) | CHRM1MAPK1ATMALDH1A1LMNA | |
| Ornidazole SCHEMBL28736392 | 0.75 | CHRM1 (0.97) | CHRM1MAPK1ATMALDH1A1LMNA | |
| Ornidazole SCHEMBL28751635 | 0.75 | CHRM1 (0.97) | CHRM1MAPK1ATMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220288086-A1 | TREATMENT FOR BACTERIAL INFECTION | VYOME THERAPEUTICS LIMITED (IN) | 2022-09-15 | — | — | US | disclosed |
| US-20160346294-A1 | TREATMENTS FOR RESISTANT ACNE | VYOME BIOSCIENCES PVT. LTD. (IN) | 2016-12-01 | — | — | US | disclosed |
| US-20160346294-A1 | TREATMENTS FOR RESISTANT ACNE | VYOME BIOSCIENCES PVT. LTD. (IN) | 2016-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220288086-A1 | TREATMENT FOR BACTERIAL INFECTION | ELANE, CFTR, TLR5 | CHRM1 4822/4885MAPK1 2754/4885ATM 2133/4885 |
| US-20160346294-A1 | TREATMENTS FOR RESISTANT ACNE | CUTA, RARB, RARG | CHRM1 4875/4885MAPK1 1903/4885ATM 1660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.