Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.68 |
| ▸ | EGFR | P00533 | 5/20 | 0.56 |
| ▸ | TEC | P42680 | 3/20 | 0.51 |
| ▸ | BMX | P51813 | 3/20 | 0.51 |
| ▸ | TXK | P42681 | 2/20 | 0.51 |
| ▸ | LYN | P07948 | 2/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.51 |
| ▸ | ITK | Q08881 | 2/20 | 0.51 |
| ▸ | BLK | P51451 | 2/20 | 0.51 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.51 |
| ▸ | LATS1 | O95835 | 1/20 | 0.51 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CSF1R | P07333 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18269040 | 0.90 | BTK (0.67) | BTKEGFRTECBMXTXK | |
| SCHEMBL18269167 | 0.89 | BTK (0.54) | BTKEGFRABL1RETHCK | |
| SCHEMBL18269003 | 0.89 | BTK (0.68) | BTKEGFRTECBMXTXK | |
| SCHEMBL18268844 | 0.88 | EGFR (0.74) | BTKEGFRTECBMXTXK | |
| SCHEMBL18269166 | 0.86 | BTK (0.52) | BTKEGFRLYNNUDT14LCK | |
| SCHEMBL18268694 | 0.84 | BTK (0.59) | BTKEGFRTECBMXLYN | |
| SCHEMBL18268650 | 0.84 | BTK (0.68) | BTKEGFRTECBMXLYN | |
| SCHEMBL18269169 | 0.84 | EGFR (0.49) | BTKEGFRTECBMXTXK | |
| SCHEMBL18269002 | 0.84 | FGFR2 (0.62) | BTKEGFRFGFR2ITKLCK | |
| SCHEMBL15613529 | 0.83 | BTK (0.61) | BTKEGFRLYNNUDT14ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179210-A1 | Inhibitors of the TEC Kinase Enzyme Family | PHARMASCIENCE INC. (CA) | 2018-06-28 | — | — | US | disclosed |
| WO-2016187723-A1 | INHIBITORS OF THE TEC KINASE ENZYME FAMILY | PHARMASCIENCE INC. (CA) | 2016-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179210-A1 | Inhibitors of the TEC Kinase Enzyme Family | TEC, BTK, LCK | BTK 2/4885EGFR 671/4885TEC 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.