Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.52 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.46 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.46 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18269007 | 0.89 | SRC (0.57) | BTKLCKLYNPIK3CDNUDT14 | |
| SCHEMBL18269008 | 0.89 | BTK (0.52) | BTKLCKLYNPIK3CDNUDT14 | |
| SCHEMBL15613529 | 0.88 | BTK (0.61) | BTKLCKLYNPIK3CDNUDT14 | |
| SCHEMBL18268991 | 0.88 | BTK (0.55) | BTKLCKLYNPIK3CDNUDT14 | |
| SCHEMBL18268660 | 0.86 | BTK (0.53) | BTKLCKLYNPIK3CDNUDT14 | |
| SCHEMBL15613558 | 0.86 | BTK (0.52) | BTKLCKLYNPIK3CDNUDT14 | |
| SCHEMBL18268976 | 0.86 | BTK (0.68) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL18269167 | 0.85 | BTK (0.54) | BTKPIK3CDSRCKDREGFR | |
| SCHEMBL18269001 | 0.85 | BTK (0.50) | BTKLCKLYNPIK3CDNUDT14 | |
| SCHEMBL18269173 | 0.83 | BTK (0.53) | BTKLCKLYNPIK3CDNUDT14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016187723-A1 | INHIBITORS OF THE TEC KINASE ENZYME FAMILY | PHARMASCIENCE INC. (CA) | 2016-12-01 | — | — | WO | disclosed |