Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 11/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13431124 | 1.00 | HMGCR (0.74) | HMGCR | |
| SCHEMBL30571418 | 1.00 | HMGCR (0.74) | HMGCR | |
| SCHEMBL12897943 | 1.00 | HMGCR (0.74) | HMGCR | |
| SCHEMBL3221050 | 1.00 | HMGCR (0.74) | HMGCR | |
| SCHEMBL245092 | 1.00 | HMGCR (0.74) | HMGCR | |
| SCHEMBL13625375 | 1.00 | HMGCR (0.74) | HMGCR | |
| SCHEMBL14669553 | 1.00 | HMGCR (0.74) | HMGCR | |
| SCHEMBL245091 | 1.00 | HMGCR (0.74) | HMGCR | |
| SCHEMBL30571404 | 1.00 | HMGCR (0.74) | HMGCR | |
| SCHEMBL13764732 | 1.00 | HMGCR (0.74) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190315696-A1 | ROSUVASTATIN CALCIUM AND PROCESS FOR PRODUCING INTERMEDIATE THEREOF | API CORPORATION (JP) | 2019-10-17 | — | — | US | disclosed |
| US-10377722-B2 | Rosuvastatin calcium and process for producing intermediate thereof | API CORPORATION (JP) | 2019-08-13 | — | — | US | disclosed |
| US-20170305867-A1 | ROSUVASTATIN CALCIUM AND PROCESS FOR PRODUCING INTERMEDIATE THEREOF | API CORPORATION (JP) | 2017-10-26 | — | — | US | disclosed |
| US-20170305867-A1 | ROSUVASTATIN CALCIUM AND PROCESS FOR PRODUCING INTERMEDIATE THEREOF | API CORPORATION (JP) | 2017-10-26 | — | — | US | disclosed |
| US-9695130-B2 | Rosuvastatin calcium and process for producing intermediate thereof | API CORPORATION (JP) | 2017-07-04 | — | — | US | disclosed |
| US-9695130-B2 | Rosuvastatin calcium and process for producing intermediate thereof | API CORPORATION (JP) | 2017-07-04 | — | — | US | disclosed |
| US-20160347718-A1 | ROSUVASTATIN CALCIUM AND PROCESS FOR PRODUCING INTERMEDIATE THEREOF | API CORPORATION (JP) | 2016-12-01 | — | — | US | disclosed |
| US-20160347718-A1 | ROSUVASTATIN CALCIUM AND PROCESS FOR PRODUCING INTERMEDIATE THEREOF | API CORPORATION (JP) | 2016-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160347718-A1 | ROSUVASTATIN CALCIUM AND PROCESS FOR PRODUCING INTERMEDIATE THEREOF | HMGCR, COASY, PCSK9 | HMGCR 1/4885 |
| US-20170305867-A1 | ROSUVASTATIN CALCIUM AND PROCESS FOR PRODUCING INTERMEDIATE THEREOF | HMGCR, COASY, PCSK9 | HMGCR 1/4885 |
| US-10377722-B2 | Rosuvastatin calcium and process for producing intermediate thereof | HMGCR, COASY, PCSK9 | HMGCR 1/4885 |
| US-20190315696-A1 | ROSUVASTATIN CALCIUM AND PROCESS FOR PRODUCING INTERMEDIATE THEREOF | HMGCR, COASY, PCSK9 | HMGCR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.