Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16736829 | 0.93 | TYR (0.46) | TYRMAPTALOX15HTTMEN1 | |
| SCHEMBL16736747 | 0.83 | HMGCR (0.44) | TYRMAPTALOX15HTTTP53 | |
| SCHEMBL30320332 | 0.81 | ALOX15 (0.56) | TYRMAPTALOX15HTTMEN1 | |
| SCHEMBL16736687 | 0.80 | ALOX15 (0.45) | TYRMAPTALOX15HTTMEN1 | |
| SCHEMBL18272109 | 0.79 | ALOX15 (0.39) | TYRMAPTALOX15HTTTP53 | |
| SCHEMBL28795591 | 0.78 | TYR (0.47) | TYRMAPTALOX15HTTMEN1 | |
| SCHEMBL16736834 | 0.78 | TYR (0.47) | TYRMAPTALOX15HTTMEN1 | |
| SCHEMBL3408192 | 0.77 | ALOX15 (0.56) | TYRMAPTALOX15HTTMEN1 | |
| SCHEMBL16736839 | 0.77 | TYR (0.50) | TYRMAPTALOX15HTTMEN1 | |
| SCHEMBL30604741 | 0.77 | ALOX15 (0.56) | TYRMAPTALOX15HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016190871-A1 | 2,5-DIALKYL-4-H/HALO/ETHER-PHENOL COMPOUNDS | TANSNA THERAPEUTICS, INC. (US) | 2016-12-01 | — | — | WO | disclosed |