Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 13/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 11/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17577451 | 0.99 | CD274 (0.41) | CD274PDCD1KDM4ECRHR1CA12 | |
| SCHEMBL17470636 | 0.99 | CD274 (0.41) | CD274PDCD1KDM4ECRHR1CA12 | |
| SCHEMBL17470606 | 0.98 | CD274 (0.42) | CD274PDCD1KDM4ECRHR1CA12 | |
| SCHEMBL16135202 | 0.97 | CD274 (0.41) | CD274PDCD1KDM4ECRHR1CA12 | |
| SCHEMBL17470548 | 0.97 | CD274 (0.41) | CD274PDCD1KDM4ECRHR1CA12 | |
| SCHEMBL17057300 | 0.96 | CD274 (0.37) | CD274PDCD1CA12CA9 | |
| SCHEMBL17057318 | 0.96 | CD274 (0.37) | CD274PDCD1CA12CA9 | |
| SCHEMBL16135029 | 0.95 | CD274 (0.38) | CD274PDCD1KDM4EHSD17B1HSD17B2 | |
| SCHEMBL17263359 | 0.93 | CD274 (0.37) | CD274PDCD1KDM4ECRHR1CA12 | |
| SCHEMBL18022589 | 0.91 | ALOX5 (0.38) | CD274PDCD1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160351812-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2016-12-01 | — | — | US | disclosed |