SCHEMBL182733

SCHEMBL182733

C=C(CCCC)C(=O)O.N#CC=CC=Cc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.40
TDP1 Q9NUW8 2/20 0.39
LMNA P02545 2/20 0.38
KDM4E B2RXH2 2/20 0.38
EGFR P00533 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
MCL1 Q07820 2/20 0.37
CYP3A4 P08684 1/20 0.36
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
CES2 O00748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9067801 1.00 HDAC3 (0.40) HDAC3TDP1LMNAKDM4EEGFR
Ethylene SCHEMBL28301426 0.99 HDAC3 (0.40) HDAC3TDP1LMNAKDM4EEGFR
SCHEMBL8335155 0.96 LMNA (0.43) HDAC3TDP1LMNAKDM4EEGFR
SCHEMBL29471809 0.89 HDAC3 (0.48) HDAC3TDP1LMNAKDM4EEGFR
SCHEMBL6734704 0.88 MCL1 (0.37) HDAC3LMNAKDM4EKMT2AMCL1
SCHEMBL1765980 0.87 MCL1 (0.40) HDAC3TDP1LMNAKDM4EKMT2A
SCHEMBL1140851 0.84 MCL1 (0.38) HDAC3LMNAKDM4EKMT2AMCL1
SCHEMBL18171946 0.82 CYP3A4 (0.40) HDAC3TDP1LMNAKDM4EEGFR
Itaconate SCHEMBL8677282 0.82 HDAC3 (0.42) HDAC3LMNAKDM4EMEN1KMT2A
Styrene SCHEMBL183141 0.82 LMNA (0.41) HDAC3TDP1LMNAKDM4EEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012012763-A4 SLIDER AND HISTORY FIELD FOR SMART CHAT SESSIONS 24/7 CUSTOMER, INC. (US) 2012-05-18 WO claimed
EP-1812637-B1 COMPOSITE THERMOPLASTIC SHEETS INCLUDING NATURAL FIBERS AZDEL INC (US) 2012-01-04 EP claimed
US-5977234-A High-density thermoplastic moulding composition GENERAL ELECTRIC COMPANY (US) 1999-11-02 US claimed
EP-0779328-B1 High-density thermoplastic moulding composition GEN ELECTRIC (US) 1999-06-30 EP claimed
WO-1997021763-A1 HIGH-DENSITY THERMOPLASTIC MOULDING COMPOSITION GENERAL ELECTRIC COMPANY (US) 1997-06-19 WO claimed
EP-0779328-A1 High-density thermoplastic moulding composition GENERAL ELECTRIC COMPANY (US) 1997-06-18 EP claimed
US-10087297-B2 Self-extinguishing polymeric composition Versalis, S.P.A. (IT) 2018-10-02 US disclosed
EP-2920241-B1 SELF-EXTINGUISHING POLYMERIC COMPOSITION VERSALIS SPA (IT) 2017-10-25 EP disclosed
EP-2922917-B1 SELF-EXTINGUISHING POLYMERIC COMPOSITION VERSALIS SPA (IT) 2017-01-04 EP disclosed
US-20150299410-A1 SELF-EXTINGUISHING POLYMERIC COMPOSITION VERSALIS S.P.A. (IT) 2015-10-22 US disclosed
EP-2922917-A1 SELF-EXTINGUISHING POLYMERIC COMPOSITION Versalis S.p.A (IT) 2015-09-30 EP disclosed
EP-2920241-A1 SELF-EXTINGUISHING POLYMERIC COMPOSITION Versalis S.p.A (IT) 2015-09-23 EP disclosed
WO-2014080326-A1 SELF-EXTINGUISHING POLYMERIC COMPOSITION VERSALIS S.P.A (IT) 2014-05-30 WO disclosed
EP-0853585-A4 CARTON HAVING BUCKLE-CONTROLLED BRIM CURL AND METHOD AND BLANK FOR FORMING THE SAME FORT JAMES CORP (US) 1999-09-08 EP disclosed
US-5868309-A PAPERBOARD CONTAINER, STYRENE-ACRYLIC DERIVATIVE LATEX COATING; DEFECT-FREE BRIM CURL FORT JAMES CORPORATION (US) 1999-02-09 US disclosed
EP-0853585-A1 CARTON HAVING BUCKLE-CONTROLLED BRIM CURL AND METHOD AND BLANK FOR FORMING THE SAME Fort James Corporation (US) 1998-07-22 EP disclosed
EP-0771852-A2 Flame retardant thermoplastic composition containing aromatic polycarbonate resins and a rubber modified graft copolymer GENERAL ELECTRIC COMPANY (US) 1997-05-07 EP disclosed
WO-1997005024-A9 CARTON HAVING BUCKLE-CONTROLLED BRIM CURL AND METHOD AND BLANK FOR FORMING THE SAME 1997-04-17 WO disclosed
WO-1997005024-A1 CARTON HAVING BUCKLE-CONTROLLED BRIM CURL AND METHOD AND BLANK FOR FORMING THE SAME JAMES RIVER CORPORATION OF VIRGINIA (US) 1997-02-13 WO disclosed
EP-0714949-A2 Processes, thermoplastic compositions and emulsion graft copolymer utilizing a polyacid GENERAL ELECTRIC COMPANY (US) 1996-06-05 EP disclosed