Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18274524 | 1.00 | GPR119 (0.59) | GPR119 | |
| SCHEMBL15540580 | 0.93 | GPR119 (0.62) | GPR119 | |
| SCHEMBL15541294 | 0.93 | GPR119 (0.62) | GPR119 | |
| SCHEMBL15540584 | 0.93 | GPR119 (0.62) | GPR119 | |
| SCHEMBL15540582 | 0.93 | GPR119 (0.62) | GPR119 | |
| SCHEMBL9974209 | 0.85 | GPR119 (0.67) | GPR119 | |
| SCHEMBL18274523 | 0.83 | GPR119 (0.45) | GPR119 | |
| SCHEMBL15582948 | 0.81 | GPR119 (0.51) | GPR119 | |
| SCHEMBL15541321 | 0.81 | GPR119 (0.51) | GPR119 | |
| SCHEMBL15582947 | 0.81 | GPR119 (0.51) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858996-B1 | 4-(2,3-Dihydro-furo[2,3-c]pyridin-2-yl)-piperidine-1-carboxylic acid ester derivatives as G-protein-coupled receptor 119 (GPR119) agonists for the treatment of metabolic disorders, such as diabetes, dyslipidemia and obesity | BOEHRINGER INGELHEIM INT (DE) | 2016-12-07 | — | — | EP | disclosed |