SCHEMBL18274858

SCHEMBL18274858

O=S(=O)(O)c1ccc2c(O)cc(S(=O)(=O)O)cc2c1.[KH].[KH]

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 5/20 0.74
NSD2 O96028 3/20 0.74
DUSP3 P51452 2/20 0.74
PTPN5 P54829 2/20 0.74
PTPN11 Q06124 2/20 0.74
PRMT1 Q99873 2/20 0.68
NT5E P21589 3/20 0.59
CTDSP1 Q9GZU7 1/20 0.55
ALDH1A1 P00352 4/20 0.53
HSD17B10 Q99714 4/20 0.53
CYP2C9 P11712 3/20 0.53
CYP2C19 P33261 2/20 0.53
SIRT1 Q96EB6 1/20 0.51
CASP7 P55210 1/20 0.50
HPGD P15428 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP1A2 P05177 2/20 0.46
LMNA P02545 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465086 0.98 CASP6 (0.77) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL29462031 0.98 CASP6 (0.77) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL1984810 0.96 CASP6 (0.74) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL565058 0.96 CASP6 (0.74) CASP6NSD2DUSP3PTPN5PTPN11
Ammonia Solution, Strong SCHEMBL11667165 0.96 CASP6 (0.74) CASP6NSD2DUSP3PTPN5PTPN11
Potassium SCHEMBL18274860 0.96 CASP6 (0.74) CASP6NSD2DUSP3PTPN5PTPN11
Water SCHEMBL28289812 0.96 CASP6 (0.74) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL1806613 0.91 CASP6 (0.73) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL6571750 0.89 CASP6 (0.66) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL1804328 0.89 CASP6 (0.70) CASP6NSD2DUSP3PTPN5PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3101002-A1 ARYL SULFONIC ACID COMPOUND AND USE OF SAME Nissan Chemical Industries, Ltd. (JP) 2016-12-07 EP disclosed