Doconexent

Doconexent

SCHEMBL18274946

CC/C=C/C/C=C/C/C=C/C/C=C\C/C=C/C/C=C\CCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 1.00
▸ PPARG P37231 6/20 1.00
▸ CYP19A1 P11511 5/20 1.00
▸ MAPT P10636 5/20 1.00
▸ FFAR1 O14842 4/20 1.00
▸ OXER1 Q8TDS5 3/20 1.00
▸ RXRA P19793 2/20 1.00
▸ PTGS1 P23219 5/20 0.77
▸ F7 P08709 4/20 0.77
▸ F3 P13726 4/20 0.77
▸ PPARD Q03181 4/20 0.77
▸ PPARA Q07869 4/20 0.77
▸ KMT2A Q03164 3/20 0.77
▸ ADORA3 P0DMS8 1/20 0.77
▸ L3MBTL1 Q9Y468 3/20 0.71
▸ KDM4E B2RXH2 2/20 0.71
▸ MEN1 O00255 2/20 0.71
▸ LMNA P02545 2/20 0.71
▸ CYP3A4 P08684 2/20 0.71
▸ HPGD P15428 2/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2241832 1.00 ALDH1A1 (1.00) ALDH1A1PPARGCYP19A1MAPTFFAR1
Doconexent SCHEMBL18185529 1.00 ALDH1A1 (1.00) ALDH1A1PPARGCYP19A1MAPTFFAR1
Doconexent SCHEMBL18185428 1.00 ALDH1A1 (1.00) ALDH1A1PPARGCYP19A1MAPTFFAR1
Doconexent SCHEMBL288437 1.00 ALDH1A1 (1.00) ALDH1A1PPARGCYP19A1MAPTFFAR1
Doconexent SCHEMBL17289459 1.00 ALDH1A1 (1.00) ALDH1A1PPARGCYP19A1MAPTFFAR1
Doconexent SCHEMBL18185531 1.00 ALDH1A1 (1.00) ALDH1A1PPARGCYP19A1MAPTFFAR1
Doconexent SCHEMBL13900774 1.00 ALDH1A1 (1.00) ALDH1A1PPARGCYP19A1MAPTFFAR1
Doconexent SCHEMBL18185505 1.00 ALDH1A1 (1.00) ALDH1A1PPARGCYP19A1MAPTFFAR1
SCHEMBL12073579 1.00 ALDH1A1 (1.00) ALDH1A1PPARGCYP19A1MAPTFFAR1
SCHEMBL6473094 1.00 ALDH1A1 (1.00) ALDH1A1PPARGCYP19A1MAPTFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11856952-B2 Microbial oil, production method for microbial oil, concentrated microbial oil, and production method for concentrated microbial oil NIPPON SUISAN KAISHA, LTD. (JP) 2024-01-02 — — US disclosed
US-20220248671-A1 MICROBIAL OIL, PRODUCTION METHOD FOR MICROBIAL OIL, CONCENTRATED MICROBIAL OIL, AND PRODUCTION METHOD FOR CONCENTRATED MICROBIAL OIL NIPPON SUISAN KAISHA, LTD. (JP) 2022-08-11 — — US disclosed
EP-3900543-A1 MICROBIAL OIL, PRODUCTION METHOD FOR MICROBIAL OIL, CONCENTRATED MICROBIAL OIL, AND PRODUCTION METHOD FOR CONCENTRATED MICROBIAL OIL NIPPON SUISAN KAISHA, LTD. (JP) 2021-10-27 — — EP disclosed
EP-3101138-B1 MICROBIAL OIL, METHOD FOR MANUFACTURING MICROBIAL OIL, CONCENTRATED MICROBIAL OIL, AND METHOD FOR MANUFACTURING CONCENTRATED MICROBIAL OIL NIPPON SUISAN KAISHA LTD (JP) 2021-05-05 — — EP disclosed
EP-3101138-A1 MICROBIAL OIL, METHOD FOR MANUFACTURING MICROBIAL OIL, CONCENTRATED MICROBIAL OIL, AND METHOD FOR MANUFACTURING CONCENTRATED MICROBIAL OIL Nippon Suisan Kaisha, Ltd. (JP) 2016-12-07 — — EP disclosed
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