Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28525339 | 0.95 | MAPT (0.39) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL12071961 | 0.92 | HPGD (0.50) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17469340 | 0.92 | HPGD (0.50) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17776135 | 0.89 | NR1H2 (0.47) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5494939 | 0.86 | HPGD (0.52) | HPGDMAPTKMT2ARECQLEPHX1 | |
| SCHEMBL8476016 | 0.84 | NR1H2 (0.41) | MAPTALDH1A1NR1H2DDB1CRBN | |
| SCHEMBL18751745 | 0.82 | NR1H2 (0.41) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL12995623 | 0.82 | USP2 (0.49) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14698321 | 0.80 | HPGD (0.45) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL18275027 | 0.77 | HPGD (0.50) | HPGDMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12478696-B2 | Gadolinium chelate compounds for use in magnetic resonance imaging | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2025-11-25 | — | — | US | disclosed |
| US-20250114485-A1 | GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2025-04-10 | — | — | US | disclosed |
| US-20230113481-A1 | NEW GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2023-04-13 | — | — | US | disclosed |
| US-11491245-B2 | Gadolinium chelate compounds for use in magnetic resonance imaging | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-11-08 | — | — | US | disclosed |
| US-11491245-B2 | Gadolinium chelate compounds for use in magnetic resonance imaging | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-11-08 | — | — | US | disclosed |
| EP-3611169-B1 | NEW GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | Bayer Pharma AG (DE) | 2021-07-21 | — | — | EP | disclosed |
| CN-107667096-B | Novel gadolinium chelate compounds for magnetic resonance imaging | 拜耳医药股份公司 | 2021-02-02 | — | — | CN | disclosed |
| US-20200353104-A1 | GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-11-12 | — | — | US | disclosed |
| US-20200353104-A1 | GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-11-12 | — | — | US | disclosed |
| US-10722601-B2 | Gadolinium chelate compounds for use in magnetic resonance imaging | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-07-28 | — | — | US | disclosed |
| US-10722601-B2 | Gadolinium chelate compounds for use in magnetic resonance imaging | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-07-28 | — | — | US | disclosed |
| EP-3611169-A1 | NEW GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | Bayer Pharma Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| EP-3303307-B1 | NEW GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | Bayer Pharma AG (DE) | 2019-09-04 | — | — | EP | disclosed |
| US-20190083659-A1 | GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-03-21 | — | — | US | disclosed |
| US-20190083659-A1 | GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-03-21 | — | — | US | disclosed |
| US-10137209-B2 | Gadolinium chelate compounds for use in magnetic resonance imaging | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-11-27 | — | — | US | disclosed |
| US-20180169274-A1 | NEW GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-06-21 | — | — | US | disclosed |
| US-20180169274-A1 | NEW GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-06-21 | — | — | US | disclosed |
| US-20180169274-A1 | NEW GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-06-21 | — | — | US | disclosed |
| EP-3101012-A1 | NEW GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | Bayer Pharma Aktiengesellschaft (DE) | 2016-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12478696-B2 | Gadolinium chelate compounds for use in magnetic resonance imaging | GLRA1, GLRA3, GLRB | HPGD 1554/4885MAPT 347/4885ALDH1A1 3811/4885 |
| US-10722601-B2 | Gadolinium chelate compounds for use in magnetic resonance imaging | GLRA1, GLRA3, GLRB | HPGD 2096/4885MAPT 627/4885ALDH1A1 3746/4885 |
| US-11491245-B2 | Gadolinium chelate compounds for use in magnetic resonance imaging | GLRA1, GLRA3, GLRB | HPGD 1943/4885MAPT 418/4885ALDH1A1 3821/4885 |
| US-20230113481-A1 | NEW GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | GLRA1, GLRA3, GLRB | HPGD 1456/4885MAPT 514/4885ALDH1A1 3683/4885 |
| US-10137209-B2 | Gadolinium chelate compounds for use in magnetic resonance imaging | MAG, GLRX3, RXFP1 | HPGD 746/4885MAPT 2539/4885ALDH1A1 4721/4885 |
| US-20180169274-A1 | NEW GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | RXFP1, MAG, GLRX3 | HPGD 1197/4885MAPT 2346/4885ALDH1A1 4775/4885 |
| US-20200353104-A1 | GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | GLRA1, GLRA3, GLRB | HPGD 1943/4885MAPT 418/4885ALDH1A1 3821/4885 |
| US-20250114485-A1 | GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | GLRA1, GLRA3, GLRB | HPGD 1554/4885MAPT 347/4885ALDH1A1 3811/4885 |
| US-20190083659-A1 | GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | GLRA1, GLRA3, GLRB | HPGD 2096/4885MAPT 627/4885ALDH1A1 3746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.