Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18275003 | 0.95 | HPGD (0.43) | MAPTMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL12071961 | 0.87 | HPGD (0.50) | MAPTMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL17469340 | 0.87 | HPGD (0.50) | MAPTMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL17776135 | 0.84 | NR1H2 (0.47) | MAPTMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL8476016 | 0.82 | NR1H2 (0.41) | MAPTALDH1A1DDB1CRBNNR1H2 | |
| SCHEMBL5494939 | 0.82 | HPGD (0.52) | MAPTKMT2AHPGDGPR119RECQL | |
| SCHEMBL18751745 | 0.78 | NR1H2 (0.41) | MAPTMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL12995623 | 0.78 | USP2 (0.49) | MAPTMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL14698321 | 0.76 | HPGD (0.45) | MAPTMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL14635912 | 0.76 | HTT (0.38) | MEN1ALDH1A1KMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107667096-B | Novel gadolinium chelate compounds for magnetic resonance imaging | 拜耳医药股份公司 | 2021-02-02 | — | — | CN | disclosed |