Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.51 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1826266 | 0.94 | P2RX7 (0.51) | P2RX7CTSLMMP13CASP1 | |
| SCHEMBL3580679 | 0.92 | P2RX7 (0.52) | P2RX7CTSL | |
| SCHEMBL1826528 | 0.90 | P2RX7 (0.53) | P2RX7CTSL | |
| SCHEMBL1826137 | 0.89 | P2RX7 (0.50) | P2RX7CTSL | |
| SCHEMBL1824760 | 0.88 | P2RX7 (0.57) | P2RX7CTSL | |
| SCHEMBL1828101 | 0.87 | P2RX7 (0.60) | P2RX7MMP13 | |
| SCHEMBL1822339 | 0.86 | P2RX7 (0.59) | P2RX7 | |
| SCHEMBL1824533 | 0.85 | P2RX7 (0.58) | P2RX7MMP13 | |
| SCHEMBL1826061 | 0.84 | TACR1 (0.57) | P2RX7 | |
| SCHEMBL1827307 | 0.84 | P2RX7 (0.53) | P2RX7CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161254-B1 | Intermediate for preparing a biaryl compound | SUMITOMO CHEMICAL CO (JP) | 2014-08-13 | — | — | EP | disclosed |
| EP-1481967-B1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2011-05-04 | — | — | EP | disclosed |
| EP-2161254-A1 | Intermediate for preparing a biaryl compound | Sumitomo Chemical Company, Limited (JP) | 2010-03-10 | — | — | EP | disclosed |