SCHEMBL1827653

SCHEMBL1827653

CCCCCC(C=O)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.50
CTSK P43235 7/20 0.47
CTSL P07711 3/20 0.47
CTSB P07858 3/20 0.47
CTSH P09668 2/20 0.47
TSHR P16473 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CNR2 P34972 1/20 0.45
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
MMP2 P08253 5/20 0.41
MMP1 P03956 2/20 0.41
MMP3 P08254 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10629707 0.98 CSNK1E (0.53) CSNK1ECTSKCTSLCTSBCTSH
SCHEMBL25457813 0.98 CSNK1E (0.53) CSNK1ECTSKCTSLCTSBCTSH
SCHEMBL18315865 0.98 CSNK1E (0.53) CSNK1ECTSKCTSLCTSBCTSH
SCHEMBL14149558 0.98 CSNK1E (0.53) CSNK1ECTSKCTSLCTSBCTSH
SCHEMBL3366397 0.95 TSHR (0.52) CSNK1ECTSKCTSLCTSBCTSH
SCHEMBL1546515 0.87 TAAR1 (0.46) CTSKCTSLCTSBCTSHMEN1
SCHEMBL29038365 0.85 SMN1; SMN2 (0.44) CSNK1ECTSKCTSLCTSBCTSH
SCHEMBL3678439 0.83 MMP2 (0.47) MEN1KMT2ATAAR1MMP2
SCHEMBL9416071 0.83 CSNK1E (0.54) CSNK1ESMN1; SMN2CNR2MEN1KMT2A
SCHEMBL7279393 0.82 ACE (0.45) SMN1; SMN2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2844065-B1 LURE COMPOSITION ATTRATEC GMBH (DE) 2021-01-06 EP claimed
US-11998633-B2 Topical sol-gel composition for the treatment of dermatitis AMOREPACIFIC CORPORATION (KR) 2024-06-04 US disclosed
EP-2844065-B1 LURE COMPOSITION ATTRATEC GMBH (DE) 2021-01-06 EP disclosed
US-20180021467-A1 METHOD OF BLOCKING PERCEPTION OF MALODOR MONELL CHEMICAL SENSES CENTRE (US) 2018-01-25 US disclosed
CN-104496838-B Substituted ring butanes neuraminidase inhibitor and using method thereof and purposes SUNSHINE LAKE PHARMA CO.,LTD. (CN) 2016-04-20 CN disclosed
CN-104496839-B Substituted ring butanes neuraminidase inhibitor and using method thereof and purposes SUNSHINE LAKE PHARMA CO.,LTD. (CN) 2016-04-20 CN disclosed
CN-104496838-A Substituted-cyclobutane neuraminidase inhibitor as well as using method and application of substituted-cyclobutane neuraminidase inhibitor GUANGDONG HEC PHARMACEUTICAL 2015-04-08 CN disclosed
CN-104496839-A Substituted-cyclobutane neuraminidase inhibitor as well as using method and application of substituted-cyclobutane neuraminidase inhibitor GUANGDONG HEC PHARMACEUTICAL 2015-04-08 CN disclosed
EP-2844065-A2 ATTRACTANT COMPOSITION Attratec GmbH (DE) 2015-03-11 EP disclosed
WO-2013164426-A2 ATTRACTANT COMPOSITION ATTRATEC GMBH (DE) 2013-11-07 WO disclosed
WO-2009083156-A1 METHOD FOR REDUCING MALODOROUS SUBSTANCES IN TANK CONTAINERS AIR & D - SARL (FR) 2009-07-09 WO disclosed
US-5401722-A Peptide analogues MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-03-28 US disclosed
EP-0501280-A2 Renin-inhibiting peptide analogues MERCK PATENT GmbH (DE) 1992-09-02 EP disclosed
EP-0446485-A2 Peptide analogues with renininhibiting activity MERCK PATENT GmbH (DE) 1991-09-18 EP disclosed
EP-0339483-A2 Renin inhbiting amino-acid derivatives MERCK PATENT GmbH (DE) 1989-11-02 EP disclosed
EP-0327877-A2 Peptide-renininhibitors MERCK PATENT GmbH (DE) 1989-08-16 EP disclosed
EP-0292800-A2 Amino acid derivatives MERCK PATENT GmbH (DE) 1988-11-30 EP disclosed
US-4774076-A DENTIFRICES, MOUTHWASHES LION CORPORATION (JP) 1988-09-27 US disclosed
EP-0249096-A2 Renin-inhibiting amino acid derivatives MERCK PATENT GmbH (DE) 1987-12-16 EP disclosed
US-4649044-A DISCOLORATION INHIBITION LION CORPORATION (JP) 1987-03-10 US disclosed