Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.52 |
| ▸ | MDM4 | O15151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580924 | 0.92 | CASP3 (0.50) | CASP3MDM4TP53KMT2AMDM2 | |
| SCHEMBL1823327 | 0.90 | CASP3 (0.48) | CASP3MDM4TP53ATMKMT2A | |
| SCHEMBL1825168 | 0.89 | CASP3 (0.48) | CASP3ATMKMT2A | |
| SCHEMBL1823338 | 0.89 | CASP3 (0.48) | CASP3MDM4TP53KMT2AMDM2 | |
| SCHEMBL1827734 | 0.89 | BACE1 (0.48) | CASP3MDM4TP53BACE1 | |
| SCHEMBL1828175 | 0.85 | CASP3 (0.44) | CASP3KMT2AMDM2BACE1 | |
| SCHEMBL1827981 | 0.85 | CASP3 (0.44) | CASP3KMT2AMDM2BACE1 | |
| SCHEMBL119848 | 0.84 | KMT2A (0.53) | CASP3MDM4TP53ATMKMT2A | |
| SCHEMBL118281 | 0.84 | KMT2A (0.53) | CASP3MDM4TP53ATMKMT2A | |
| SCHEMBL29384904 | 0.84 | KMT2A (0.53) | CASP3MDM4TP53ATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161254-B1 | Intermediate for preparing a biaryl compound | SUMITOMO CHEMICAL CO (JP) | 2014-08-13 | — | — | EP | disclosed |
| EP-1481967-B1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2011-05-04 | — | — | EP | disclosed |
| EP-2161254-A1 | Intermediate for preparing a biaryl compound | Sumitomo Chemical Company, Limited (JP) | 2010-03-10 | — | — | EP | disclosed |