Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1825681 | 0.88 | PDE2A (0.38) | PDE2APDE4DNAMPTEPHX2PIK3CD | |
| SCHEMBL1822437 | 0.85 | PDE2A (0.43) | PDE2APDE4DNAMPTEPHX2PIK3CD | |
| SCHEMBL1822485 | 0.82 | PDE2A (0.38) | PDE2ANAMPTEPHX2MAPT | |
| SCHEMBL8491301 | 0.76 | F9 (0.42) | PDE2AMEN1KMT2AMAPT | |
| SCHEMBL1824077 | 0.76 | MAPT (0.35) | MEN1KMT2ACD38MAPT | |
| SCHEMBL1822657 | 0.76 | STING1 (0.40) | MEN1KMT2ACD38MAPT | |
| SCHEMBL1825085 | 0.75 | MAPT (0.38) | MEN1KMT2ACD38MAPT | |
| Hydrochloric Acid SCHEMBL1825087 | 0.75 | STING1 (0.39) | MEN1KMT2ACD38MAPT | |
| SCHEMBL8525069 | 0.74 | HCRTR1 (0.44) | PDE2AMEN1KMT2ANAMPTEPHX2 | |
| SCHEMBL1826191 | 0.74 | CD38 (0.36) | MEN1KMT2APDE4DCD38MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927458-B2 | Herbicide triazolylpyridine ketones | BAYER CROPSCIENCE AG (DE) | 2015-01-06 | — | — | US | disclosed |
| US-8658798-B2 | Herbicide triazolylpyridine ketones | BAYER CROPSCIENCE AG (DE) | 2014-02-25 | — | — | US | disclosed |
| US-20130296168-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | BAYER CROPSCIENCE AG (DE) | 2013-11-07 | — | — | US | disclosed |
| US-20110237800-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | BAYER CROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| EP-2185536-B1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | BAYER CROPSCIENCE AG (DE) | 2011-05-04 | — | — | EP | disclosed |
| EP-2185536-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | Bayer CropScience AG (DE) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009018925-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | BAYER CROPSCIENCE AG (DE) | 2009-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296168-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | DDT, PDK4, BCKDK | PDE2A 2592/4885MEN1 4606/4885KMT2A 590/4885 |
| US-20110237800-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | DDT, PDK4, BCKDK | PDE2A 2455/4885MEN1 4695/4885KMT2A 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.