SCHEMBL1827780

SCHEMBL1827780

NN1C=CNC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29865 0.62
SCHEMBL1426403 0.61
SCHEMBL3402842 0.61
SCHEMBL1150832 0.61
SCHEMBL2004962 0.61
Iodide SCHEMBL7541508 0.59
SCHEMBL6646557 0.54
SCHEMBL6653531 0.54
SCHEMBL7599980 0.54
SCHEMBL22993 0.46

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170010272-A1 RAPID PHENOTYPE TESTS FOR ANTITUBERCULAR DRUG SENSITIVITY AND RESISTANCE TRIAD NATIONAL SECURITY, LLC 2017-01-12 US claimed
WO-2015126922-A2 RAPID PHENOTYPE TESTS FOR ANTITUBERCULAR DRUG SENSITIVITY AND RESISTANCE STC. UNM (US) 2015-08-27 WO claimed
EP-1066286-A4 HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2004-02-11 EP claimed
EP-1066286-A1 HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2001-01-10 EP claimed
WO-1999045009-A1 HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 1999-09-10 WO claimed
CN-119899188-A METTL3 inhibitors 杭州邦顺制药有限公司 2025-04-29 CN disclosed
CN-119059967-A Diaryl amine compound with affinity with Tau protein, and preparation method and application thereof 北京师范大学 2024-12-03 CN disclosed
CN-115697997-B Substituted 3-phenoxyazetidin-1-yl-pyrazines having GPR52 agonistic activity 勃林格殷格翰国际有限公司 2024-07-30 CN disclosed
CN-118369411-A Microelectronic device cleaning compositions 恩特格里斯公司 2024-07-19 CN disclosed
EP-4126850-B1 SUBSTITUTED 3-PHENOXYAZETIDIN-1-YL-PYRAZINES HAVING GPR52 AGONISTIC ACTIVITY BOEHRINGER INGELHEIM INT (DE) 2024-04-17 EP disclosed
US-11780827-B2 Substituted 3-phenoxyazetidin-1-yl-pyrazines BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2023-10-10 US disclosed
WO-2023186065-A1 A CYCLIN-DEPENDENT KINASE INHIBITOR Taizhou Eoc Pharma Co., Ltd. (CN) 2023-10-05 WO disclosed
EP-1373261-A2 CYCLOPROPAHETEROCYCLES AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS MEDIVIR AB (SE) 2004-01-02 EP disclosed
US-20030187266-A1 Non-nucleoside reverse transcriptase inhibitors MEDIVIR AB (SE) 2003-10-02 US disclosed
US-20030069224-A1 Non-nucleoside reverse transcriptase inhibitors MEDIVIR AB (SE) 2003-04-10 US disclosed
WO-2002070516-A2 CYCLOPROPAHETEROCYCLES AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS MEDIVIR AB (SE) 2002-09-12 WO disclosed
EP-1066286-A1 HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2001-01-10 EP disclosed
WO-1999045009-A1 HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 1999-09-10 WO disclosed
US-4916131-A IMMUNOSUPPRESSANT SCHERING CORPORATION (US) 1990-04-10 US disclosed
US-4775686-A Naphthyridine derivatives and method for treating allergic reactions SCHERING CORPORATION (US) 1988-10-04 US disclosed