⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18243614 | 0.96 | — | — | |
| SCHEMBL28737261 | 0.67 | — | — | |
| SCHEMBL2326 | 0.62 | — | — | |
| SCHEMBL7423139 | 0.61 | — | — | |
| SCHEMBL7265385 | 0.61 | — | — | |
| SCHEMBL23437060 | 0.61 | — | — | |
| SCHEMBL9595434 | 0.61 | — | — | |
| SCHEMBL28735929 | 0.61 | — | — | |
| SCHEMBL1618754 | 0.61 | — | — | |
| SCHEMBL17800677 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4923993-A | Process for the preparation of 2-pyridinecarboxylic acid derivatives and 1-amino-1,4-dihydropyridine-2-carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-05-08 | — | — | US | claimed |
| EP-1196383-B1 | PROCESS FOR PREPARING AMLODIPINE BENZENESULPHONATE | RICHTER GEDEON VEGYESZET (HU) | 2004-12-01 | — | — | EP | disclosed |
| US-6596874-B1 | Salt formation by reaction using benzenesulfonic acid | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2003-07-22 | — | — | US | disclosed |
| EP-1196383-A1 | PROCESS FOR PREPARING AMLODIPINE BENZENESULPHONATE | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001002360-A1 | PROCESS FOR PREPARING AMLODIPINE BENZENESULPHONATE | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2001-01-11 | — | — | WO | disclosed |
| US-4923993-A | Process for the preparation of 2-pyridinecarboxylic acid derivatives and 1-amino-1,4-dihydropyridine-2-carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-05-08 | — | — | US | disclosed |