Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.80 |
| ▸ | PGR | P06401 | 2/20 | 0.80 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | AR | P10275 | 1/20 | 0.80 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.75 |
| ▸ | NR3C1 | P04150 | 9/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.72 |
| ▸ | SHBG | P04278 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472390 | 0.93 | HIF1A (0.71) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL13692155 | 0.93 | HIF1A (0.79) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL8722422 | 0.91 | HIF1A (0.73) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL8722429 | 0.91 | HIF1A (0.73) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL3999010 | 0.91 | HIF1A (0.86) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL4097766 | 0.90 | HIF1A (0.75) | HIF1APGRSERPINA6LMNAAR | |
| Hydrocortisone SCHEMBL6447755 | 0.90 | HIF1A (0.81) | HIF1APGRSERPINA6LMNAAR | |
| Hydrocortisone SCHEMBL4932219 | 0.90 | HIF1A (0.81) | HIF1APGRSERPINA6LMNAAR | |
| Iodide SCHEMBL8726967 | 0.89 | HIF1A (0.71) | HIF1APGRSERPINA6LMNAAR | |
| Iodide SCHEMBL8726973 | 0.89 | HIF1A (0.71) | HIF1APGRSERPINA6LMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230346598-A1 | AB EXTERNO INTRAOCULAR SHUNT PLACEMENT | AQUESYS, INC. | 2023-11-02 | — | — | US | disclosed |
| CN-112998944-B | External ocular shunt placement | 阿奎西斯公司 | 2023-08-22 | — | — | CN | disclosed |
| US-11612517-B2 | Ab externo intraocular shunt placement | AQUESYS, INC. (US) | 2023-03-28 | — | — | US | disclosed |
| CN-112998944-A | Ex-ocular shunt placement | 阿奎西斯公司 | 2021-06-22 | — | — | CN | disclosed |
| CN-107835678-B | Ex-ocular shunt placement | 阿奎西斯公司 | 2021-03-09 | — | — | CN | disclosed |
| US-20200261271-A1 | INTRAOCULAR DRUG DELIVERY | AQUESYS, INC. | 2020-08-20 | — | — | US | disclosed |
| US-10667947-B2 | Intraocular drug delivery | AQUESYS, INC. (US) | 2020-06-02 | — | — | US | disclosed |
| US-20200069469-A1 | AB EXTERNO INTRAOCULAR SHUNT PLACEMENT | AQUESYS, INC. | 2020-03-05 | — | — | US | disclosed |
| US-10470927-B2 | AB externo intraocular shunt placement | AQUESYS, INC. (US) | 2019-11-12 | — | — | US | disclosed |
| US-10463537-B2 | Ab externo intraocular shunt placement | AQUESYS INC. (US) | 2019-11-05 | — | — | US | disclosed |
| EP-3463228-A1 | INTRAOCULAR DRUG DELIVERY | Aquesys, Inc. (US) | 2019-04-10 | — | — | EP | disclosed |
| EP-3302381-A1 | AB EXTERNO INTRAOCULAR SHUNT PLACEMENT | Aquesys, Inc. (US) | 2018-04-11 | — | — | EP | disclosed |
| US-20170348150-A1 | INTRAOCULAR DRUG DELIVERY | AQUESYS, INC. | 2017-12-07 | — | — | US | disclosed |
| WO-2017210627-A1 | INTRAOCULAR DRUG DELIVERY | AQUESYS, INC. (US) | 2017-12-07 | — | — | WO | disclosed |
| US-20160354244-A1 | AB EXTERNO INTRAOCULAR SHUNT PLACEMENT | AQUESYS, INC. | 2016-12-08 | — | — | US | disclosed |
| WO-2016196841-A1 | AB EXTERNO INTRAOCULAR SHUNT PLACEMENT | AQUESYS, INC. (US) | 2016-12-08 | — | — | WO | disclosed |
| US-20160354245-A1 | AB EXTERNO INTRAOCULAR SHUNT PLACEMENT | AQUESYS, INC. | 2016-12-08 | — | — | US | disclosed |
| CN-102134269-A | Nitrooxy derivatives of glucocorticoids | NICOX SA | 2011-07-27 | — | — | CN | disclosed |
| CN-101300265-A | Nitro-acyloxy glucocorticoid derivatives | NICOX SA (FR) | 2008-11-05 | — | — | CN | disclosed |