Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31425749 | 1.00 | BRD4 (0.35) | BRD4CHRNB2CHRNA4PDK2PDK4 | |
| Hydrochloric Acid SCHEMBL16393577 | 0.99 | BRD4 (0.35) | BRD4CHRNB2CHRNA4PDK2PDK4 | |
| SCHEMBL20943525 | 0.86 | BRD4 (0.34) | BRD4 | |
| Hydrochloric Acid SCHEMBL16393601 | 0.85 | BRD4 (0.30) | BRD4 | |
| Hydrochloric Acid SCHEMBL16393800 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL16393852 | 0.84 | PARP14 (0.40) | PDK2PDK4HTR2B | |
| SCHEMBL20943547 | 0.83 | HTR7 (0.33) | BRD4HTR1AHTR7 | |
| SCHEMBL20943521 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL16393486 | 0.82 | HTR7 (0.33) | BRD4HTR1AHTR7 | |
| SCHEMBL2152789 | 0.82 | BRD4 (0.32) | BRD4CHRNB2CHRNA4HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022233-B1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2019-05-01 | — | — | EP | claimed |
| WO-2016197014-A1 | CATALYST SYSTEM CONTAINING HIGH SURFACE AREA SUPPORTS AND SEQUENTIAL POLYMERIZATION TO PRODUCE HETEROPHASIC POLYMERS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2016-12-08 | — | — | WO | disclosed |