Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | RRM1 | P23921 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18281190 | 1.00 | DPP7 (0.40) | DPP7GABRR1DPP9DPP4RRM1 | |
| SCHEMBL8183815 | 0.86 | GSR (0.48) | DPP7DPP9DPP4GSRDPP8 | |
| SCHEMBL2280440 | 0.85 | GSR (0.57) | DPP7DPP9DPP4GSRDPP8 | |
| Hydrochloric Acid SCHEMBL8078485 | 0.83 | GSR (0.55) | DPP7DPP9DPP4GSRDPP8 | |
| Hydrochloric Acid SCHEMBL14311789 | 0.83 | GSR (0.55) | DPP7DPP9DPP4GSRDPP8 | |
| Hydrochloric Acid SCHEMBL21931161 | 0.83 | GSR (0.55) | DPP7DPP9DPP4GSRDPP8 | |
| SCHEMBL8207593 | 0.81 | SLC1A2 (0.42) | DPP7DPP9DPP4DPP8 | |
| SCHEMBL11342489 | 0.81 | SLC1A2 (0.42) | DPP7DPP9DPP4DPP8 | |
| SCHEMBL13745633 | 0.81 | DPP4 (0.39) | DPP9DPP4NOS3NOS1NOS2 | |
| SCHEMBL13745182 | 0.81 | DPP4 (0.39) | DPP9DPP4NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016196393-A2 | AUTOPHAGY-INHIBITING COMPOUNDS AND USES THEREOF | PRESAGE BIOSCIENCES, INC. (US) | 2016-12-08 | — | — | WO | disclosed |