SCHEMBL8207593

SCHEMBL8207593

CCC[C@H](N)C(=O)N(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC1A2 P43004 3/20 0.42
▸ SLC1A1 P43005 3/20 0.42
▸ SLC1A3 P43003 2/20 0.42
▸ GRIK1 P39086 2/20 0.42
▸ GRIK2 Q13002 2/20 0.42
▸ DPP4 P27487 2/20 0.39
▸ DPP9 Q86TI2 2/20 0.39
▸ DPP7 Q9UHL4 2/20 0.38
▸ DPP8 Q6V1X1 1/20 0.38
▸ CHRM1 P11229 1/20 0.37
▸ AKR1A1 P14550 1/20 0.37
▸ CHRM3 P20309 1/20 0.37
▸ HTR2A P28223 1/20 0.37
▸ HTR2C P28335 1/20 0.37
▸ ADRA1A P35348 1/20 0.37
▸ HRH1 P35367 1/20 0.37
▸ DRD3 P35462 1/20 0.37
▸ SLC6A3 Q01959 1/20 0.37
▸ HDAC1 Q13547 1/20 0.37
▸ HDAC2 Q92769 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11342489 1.00 SLC1A2 (0.42) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL4594561 0.86 DPP7 (0.48) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL4594803 0.86 DPP7 (0.48) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL30312063 0.83 GRIK1 (0.49) SLC1A2SLC1A1GRIK1GRIK2DPP7
SCHEMBL31754346 0.82 SLC1A2 (0.39) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL13745633 0.81 DPP4 (0.39) DPP4DPP9
SCHEMBL18281192 0.81 DPP7 (0.40) DPP4DPP9DPP7DPP8
SCHEMBL13745182 0.81 DPP4 (0.39) DPP4DPP9
SCHEMBL18281190 0.81 DPP7 (0.40) DPP4DPP9DPP7DPP8
SCHEMBL2929108 0.80 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331750-A1 Preparation Method for Glufosinate LIER CHEMICAL CO., LTD. (CN) 2023-10-19 — — US disclosed
EP-3615019-A1 MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF Navitor Pharmaceuticals, Inc. (US) 2020-03-04 — — EP disclosed
WO-2018200625-A1 MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF NAVITOR PHARMACEUTICALS, INC. (US) 2018-11-01 — — WO disclosed
EP-3364958-A1 MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF Navitor Pharmaceuticals, Inc. (US) 2018-08-29 — — EP disclosed
WO-2017070518-A1 MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF NAVITOR PHARMACEUTICALS, INC. (US) 2017-04-27 — — WO disclosed
US-6107300-A CORTICOTROPIN RELEASING FACTOR ANTAGONIST; PSYCHOLOGICAL DISORDERS DUPONT PHARMACEUTICALS (US) 2000-08-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331750-A1 Preparation Method for Glufosinate GLUL, ASNS, GDA SLC1A2 540/4885SLC1A1 541/4885SLC1A3 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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