Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18288123 | 1.00 | MIF (0.51) | MIFNPC1RAB9ARECQLSMN1; SMN2 | |
| SCHEMBL18281734 | 1.00 | MIF (0.51) | MIFNPC1RAB9ARECQLSMN1; SMN2 | |
| SCHEMBL21339831 | 0.86 | MIF (0.52) | MIFNPC1RAB9ARECQLSMN1; SMN2 | |
| SCHEMBL31341175 | 0.86 | MIF (0.52) | MIFNPC1RAB9ARECQLSMN1; SMN2 | |
| SCHEMBL7372333 | 0.86 | MIF (0.52) | MIFNPC1RAB9ARECQLSMN1; SMN2 | |
| SCHEMBL2744305 | 0.86 | MIF (0.52) | MIFNPC1RAB9ARECQLSMN1; SMN2 | |
| SCHEMBL13055402 | 0.82 | CYP17A1 (0.59) | SMN1; SMN2CYP17A1PSMB8NAMPTMAP4K4 | |
| SCHEMBL418939 | 0.81 | CYP17A1 (0.54) | MIFNPC1RAB9ARECQLSMN1; SMN2 | |
| SCHEMBL1672145 | 0.80 | CYP17A1 (0.49) | MIFNPC1RAB9ARECQLSMN1; SMN2 | |
| SCHEMBL596258 | 0.78 | HDAC3 (0.50) | MIFNPC1RAB9ARECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303285-B1 | PESTICIDALLY ACTIVE OXIME AND HYDRAZONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-19 | — | — | EP | disclosed |
| EP-3303285-B1 | PESTICIDALLY ACTIVE OXIME AND HYDRAZONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-19 | — | — | EP | disclosed |
| US-10336691-B2 | Pesticidally active oxime and hydrazone derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2019-07-02 | — | — | US | disclosed |
| US-10336691-B2 | Pesticidally active oxime and hydrazone derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2019-07-02 | — | — | US | disclosed |
| US-20180141898-A1 | PESTICIDALLY ACTIVE OXIME AND HYDRAZONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-24 | — | — | US | disclosed |
| US-20180141898-A1 | PESTICIDALLY ACTIVE OXIME AND HYDRAZONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-24 | — | — | US | disclosed |
| US-20180141898-A1 | PESTICIDALLY ACTIVE OXIME AND HYDRAZONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-24 | — | — | US | disclosed |
| EP-3303285-A1 | PESTICIDALLY ACTIVE OXIME AND HYDRAZONE DERIVATIVES | Syngenta Participations AG (CH) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016193284-A1 | PESTICIDALLY ACTIVE OXIME AND HYDRAZONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-08 | — | — | WO | disclosed |
| WO-2016193284-A1 | PESTICIDALLY ACTIVE OXIME AND HYDRAZONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141898-A1 | PESTICIDALLY ACTIVE OXIME AND HYDRAZONE DERIVATIVES | ACHE, CAT, DDT | MIF 1780/4885NPC1 4360/4885RAB9A 1412/4885 |
| US-10336691-B2 | Pesticidally active oxime and hydrazone derivatives | ACHE, CAT, DDT | MIF 1780/4885NPC1 4360/4885RAB9A 1412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.