⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18282304 | 0.91 | FNTA (0.32) | — | |
| SCHEMBL18282052 | 0.89 | KDM4E (0.36) | — | |
| SCHEMBL18282045 | 0.88 | MYC (0.36) | — | |
| SCHEMBL18282255 | 0.88 | MAPT (0.32) | — | |
| SCHEMBL18282084 | 0.86 | MEN1 (0.38) | — | |
| SCHEMBL18281998 | 0.86 | XIAP (0.32) | — | |
| SCHEMBL18282152 | 0.86 | SLC6A3 (0.34) | — | |
| SCHEMBL18282217 | 0.86 | TSHR (0.34) | — | |
| SCHEMBL18282173 | 0.85 | FNTA (0.34) | — | |
| SCHEMBL18282157 | 0.84 | NPC1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12150934-B2 | Methods of using substituted pyrazole and pyrazole compounds and for treatment of hyperproliferative diseases | BANTAM PHARMACEUTICAL, LLC (US) | 2024-11-26 | — | — | US | disclosed |
| US-11602526-B2 | Substituted pyrazole and pyrrole compounds and methods for using them for inhibition of initiation of translation and treatment of diseases and disorders relating thereto | BANTAM PHARMACEUTICAL, LLC (US) | 2023-03-14 | — | — | US | disclosed |
| US-20200261424-A1 | Substituted Pyrazole and Pyrrole Compounds and Methods for Using Them for Inhibition of Initiation of Translation and Treatment of Diseases and Disorders Relating Thereto | BANTAM PHARMACEUTICAL, LLC | 2020-08-20 | — | — | US | disclosed |
| US-20200069656-A1 | Methods of Using Substituted Pyrazole and Pyrazole Compounds and for Treatment of Hyperproliferative Diseases | BANTAM PHARMACEUTICAL, LLC | 2020-03-05 | — | — | US | disclosed |
| CN-110769823-A | Methods of using substituted pyrazole and pyrrole compounds and treating hyperproliferative diseases | 班塔姆制药有限责任公司 | 2020-02-07 | — | — | CN | disclosed |
| EP-3548024-A2 | METHODS OF USING SUBSTITUTED PYRAZOLE AND PYRAZOLE COMPOUNDS AND FOR TREATMENT OF HYPERPROLIFERATIVE DISEASES | Bantam Pharmaceutical, LLC (US) | 2019-10-09 | — | — | EP | disclosed |
| US-20180311218-A1 | Substituted Pyrazole and Pyrrole Compounds and Methods for Using Them for Inhibition of Initiation of Translation and Treatment of Diseases and Disorders Relating Thereto | EGENIX, INC. | 2018-11-01 | — | — | US | disclosed |
| WO-2018102452-A2 | METHODS OF USING SUBSTITUTED PYRAZOLE AND PYRAZOLE COMPOUNDS AND FOR TREATMENT OF HYPERPROLIFERATIVE DISEASES | BANTAM PHARMACEUTICAL, LLC (US) | 2018-06-07 | — | — | WO | disclosed |
| EP-3303332-A1 | SUBSTITUTED PYRAZOLE AND PYRROLE COMPOUNDS AND METHODS FOR USING THEM FOR INHIBITION OF INITIATION OF TRANSLATION AND TREATMENT OF DISEASES AND DISORDERS RELATING THERETO | Bantam Pharmaceutical, LLC (US) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016196644-A1 | SUBSTITUTED PYRAZOLE AND PYRROLE COMPOUNDS AND METHODS FOR USING THEM FOR INHIBITION OF INITIATION OF TRANSLATION AND TREATMENT OF DISEASES AND DISORDERS RELATING THERETO | BANTAM PHARMACEUTICAL, LLC (US) | 2016-12-08 | — | — | WO | disclosed |