SCHEMBL1828449

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12305425	1.00	MDM2 (0.82)	MDM2CYP2D6CYP3A4
	SCHEMBL1819470	0.91	MDM2 (1.00)	MDM2CYP2D6CYP3A4
	SCHEMBL1819888	0.89	MDM2 (1.00)	MDM2CYP2D6CYP3A4
	SCHEMBL2459937	0.89	MDM2 (1.00)	MDM2CYP2D6CYP3A4
	SCHEMBL7989560	0.89	MDM2 (1.00)	MDM2CYP2D6CYP3A4
	SCHEMBL17360615	0.86	MDM2 (0.68)	MDM2CYP2D6CYP3A4
	SCHEMBL20100158	0.85	MDM2 (0.62)	MDM2
	SCHEMBL1823371	0.85	MDM2 (0.88)	MDM2CYP2D6CYP3A4
	SCHEMBL18569130	0.85	MDM2 (0.88)	MDM2CYP2D6CYP3A4
	SCHEMBL2455286	0.85	MDM2 (0.88)	MDM2CYP2D6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.