Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.32 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18285363 | 0.94 | PDE4B (0.35) | CNR1CNR2ANO1PDE4BPDE4A | |
| SCHEMBL18285369 | 0.89 | PDE4B (0.38) | CNR1CNR2ANO1PDE4BPDE4A | |
| SCHEMBL18285368 | 0.89 | CNR2 (0.38) | CNR1CNR2ANO1MAPTPDE4B | |
| SCHEMBL18285318 | 0.88 | ANO1 (0.39) | CNR1CNR2ANO1MAPTL3MBTL1 | |
| SCHEMBL18285307 | 0.84 | CNR2 (0.42) | CNR1CNR2ANO1PDE4BPDE4A | |
| SCHEMBL18285317 | 0.82 | CNR2 (0.46) | CNR1CNR2ANO1 | |
| SCHEMBL18285299 | 0.81 | CNR1 (0.43) | CNR1ANO1PDE4BPDE4APDE4C | |
| SCHEMBL18285329 | 0.81 | CNR1 (0.41) | CNR1CNR2ANO1MAPTPDE4B | |
| SCHEMBL18285304 | 0.79 | CNR1 (0.42) | CNR1ANO1 | |
| SCHEMBL18285358 | 0.78 | P2RX3 (0.35) | CNR1ANO1PDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303299-A1 | IMIDAZOLE DERIVATIVES | H. Hoffnabb-La Roche Ag (CH) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016193235-A1 | IMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2016-12-08 | — | — | WO | disclosed |