⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24465796 | 0.78 | — | — | |
| SCHEMBL17676886 | 0.78 | — | — | |
| SCHEMBL3048131 | 0.78 | — | — | |
| SCHEMBL24233686 | 0.75 | — | — | |
| SCHEMBL1549683 | 0.75 | — | — | |
| SCHEMBL21669915 | 0.73 | — | — | |
| SCHEMBL21662743 | 0.73 | — | — | |
| SCHEMBL23790935 | 0.73 | CYP2D6 (0.37) | — | |
| SCHEMBL6387751 | 0.73 | — | — | |
| SCHEMBL1137792 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318363-A1 | HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS | Nuevolution A/S (DK) | 2011-05-11 | — | — | EP | claimed |
| WO-2009152824-A1 | HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS | NUEVOLUTION A/S (DK) | 2009-12-23 | — | — | WO | claimed |
| CN-118302155-A | Method for freezing and freeze-drying Lipid Nanoparticles (LNPs) and LNPs obtained thereby | 赛诺菲 | 2024-07-05 | — | — | CN | disclosed |
| EP-3687999-A1 | RAPAMYCIN DERIVATIVES | Novartis AG (CH) | 2020-08-05 | — | — | EP | disclosed |
| WO-2020017608-A1 | VIRUS MEASURING METHOD, VIRUS MEASURING DEVICE, VIRUS DETERMINING PROGRAM, STRESS DETERMINING METHOD, AND STRESS DETERMINING DEVICE | 国立大学法人大阪大学 | 2020-01-23 | — | — | WO | disclosed |
| WO-2019064182-A1 | RAPAMYCIN DERIVATIVES | NOVARTIS AG (CH) | 2019-04-04 | — | — | WO | disclosed |
| WO-2017164813-A1 | ION PAIR CATALYSIS OF TUNGSTATE AND MOLYBDATE | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2017-09-28 | — | — | WO | disclosed |
| EP-2576507-A1 | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011151808-A1 | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2011-12-08 | — | — | WO | disclosed |
| EP-2318363-A1 | HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS | Nuevolution A/S (DK) | 2011-05-11 | — | — | EP | disclosed |
| WO-2009152824-A1 | HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS | NUEVOLUTION A/S (DK) | 2009-12-23 | — | — | WO | disclosed |