Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.60 |
| ▸ | BRAF | P15056 | 14/20 | 0.52 |
| ▸ | FYN | P06241 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12056878 | 1.00 | CSF1R (0.60) | CSF1RBRAFFYN | |
| SCHEMBL12056831 | 1.00 | CSF1R (0.60) | CSF1RBRAFFYN | |
| SCHEMBL12065013 | 0.93 | CSF1R (0.62) | CSF1RBRAFFYN | |
| SCHEMBL12056834 | 0.88 | CSF1R (0.79) | CSF1RBRAF | |
| SCHEMBL12056891 | 0.88 | CSF1R (0.79) | CSF1RBRAF | |
| SCHEMBL12065009 | 0.88 | FYN (0.54) | CSF1RBRAFFYN | |
| SCHEMBL12056838 | 0.88 | FYN (0.54) | CSF1RBRAFFYN | |
| SCHEMBL18286648 | 0.88 | FYN (0.54) | CSF1RBRAFFYN | |
| SCHEMBL12056844 | 0.87 | CSF1R (0.51) | CSF1RBRAFFYN | |
| SCHEMBL12056828 | 0.87 | CSF1R (0.51) | CSF1RBRAFFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569917-B1 | PYRAZINE-BASED TUBULIN INHIBITORS | YM BIOSCIENCES AUSTRALIA PTY (AU) | 2016-12-07 | — | — | EP | disclosed |